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ZIRC
ZFIN ID: ZDB-FISH-150901-29590
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Fish name: pink1sh397/sh397
Genotype: pink1sh397/sh397
Targeting Reagent: none
HUMAN DISEASE MODELED by pink1sh397/sh397
Human Disease Conditions Citations
early-onset Parkinson's disease standard conditions Soman et al., 2017
GENE EXPRESSION
Gene expression in pink1sh397/sh397
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in pink1sh397/sh397
Phenotype Conditions Figures
diencephalon has fewer parts of type diencephalon dopaminergic neuron, abnormal standard conditions Fig. 2 with image, Fig. 3 with image from Soman et al., 2017
diencephalon has number of diencephalon dopaminergic neuron, ameliorated chemical treatment by environment: ruthenium red Fig. 2 with image from Soman et al., 2017
dopaminergic neuron decreased amount, abnormal standard conditions Fig. 2, Fig. 3, Fig. 7 from Flinn et al., 2013
dopaminergic neuron differentiation process quality, abnormal standard conditions Fig. 2, Fig. 3, Fig. 7 from Flinn et al., 2013
microglial cell activation increased process quality, abnormal standard conditions Fig. 9 from Flinn et al., 2013
mitochondrial electron transport, NADH to ubiquinone decreased rate, abnormal standard conditions Fig. 4, Fig. 8 from Flinn et al., 2013
mitochondrial electron transport, ubiquinol to cytochrome c decreased rate, abnormal standard conditions Fig. 4, Fig. 8 from Flinn et al., 2013
muscle mitochondrion decreased functionality, abnormal standard conditions Fig. 4 from Flinn et al., 2013
muscle mitochondrion increased size, abnormal standard conditions Fig. 5 from Flinn et al., 2013
whole organism micu1 expression increased amount, abnormal standard conditions Fig. 3 with image from Soman et al., 2017
whole organism NADH dehydrogenase (ubiquinone) activity decreased occurrence, abnormal standard conditions Fig. 2 with image from Soman et al., 2017

CITATIONS  (4)