ZFIN Fish: pink1^sh397/sh397

ZFIN ID: ZDB-FISH-150901-29590

ZFIN ID: ZDB-FISH-150901-29590

HUMAN DISEASE MODELED by pink1^sh397/sh397

Human Disease	Conditions	Citations
early-onset Parkinson's disease	standard conditions	Soman et al., 2017

GENE EXPRESSION
Gene expression in pink1^sh397/sh397

RNA expression

Expressed Gene	Structure	Conditions	Figures
apoeb	microglial cell	standard conditions	Fig. 9 from Flinn et al., 2013
mcu	whole organism	standard conditions	Fig. 1 from Soman et al., 2017
micu1	whole organism	standard conditions	Fig. 3 from Soman et al., 2017
micu2	whole organism	standard conditions	Fig. 3 from Soman et al., 2017
smdt1a	whole organism	standard conditions	Fig. 3 from Soman et al., 2017
th	diencephalon dopaminergic neuron dopaminergic neuron	standard conditions	Fig. 2 from Soman et al., 2017 Fig. 2 from Flinn et al., 2013
tigarb	brain	standard conditions	Fig. 6 from Flinn et al., 2013
zgc:165532	whole organism	standard conditions	Fig. 3 from Soman et al., 2017

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in pink1^sh397/sh397

Phenotype	Conditions	Figures
diencephalon has fewer parts of type diencephalon dopaminergic neuron, abnormal	standard conditions	Fig. 2 , Fig. 3 from Soman et al., 2017
diencephalon has number of diencephalon dopaminergic neuron, ameliorated	chemical treatment by environment: ruthenium red	Fig. 2 from Soman et al., 2017
dopaminergic neuron decreased amount, abnormal	standard conditions	Fig. 2, Fig. 3, Fig. 7 from Flinn et al., 2013
dopaminergic neuron differentiation process quality, abnormal	standard conditions	Fig. 2, Fig. 3, Fig. 7 from Flinn et al., 2013
microglial cell activation increased process quality, abnormal	standard conditions	Fig. 9 from Flinn et al., 2013
mitochondrial electron transport, NADH to ubiquinone decreased rate, abnormal	standard conditions	Fig. 4, Fig. 8 from Flinn et al., 2013
mitochondrial electron transport, ubiquinol to cytochrome c decreased rate, abnormal	standard conditions	Fig. 4, Fig. 8 from Flinn et al., 2013
muscle mitochondrion decreased functionality, abnormal	standard conditions	Fig. 4 from Flinn et al., 2013
muscle mitochondrion increased size, abnormal	standard conditions	Fig. 5 from Flinn et al., 2013
whole organism micu1 expression increased amount, abnormal	standard conditions	Fig. 3 from Soman et al., 2017
whole organism NADH dehydrogenase (ubiquinone) activity decreased occurrence, abnormal	standard conditions	Fig. 2 from Soman et al., 2017

CITATIONS (4)