FISH
WT + MO1-exosc3
- ID
- ZDB-FISH-150901-29186
- Name
- WT + MO1-exosc3
- Genotype
- WT
- Targeting Reagent
- MO1-exosc3
Human Disease modelled by WT + MO1-exosc3
RNA Expression
Protein Expression
Reporter Gene Expression
- Francois-Moutal, L., Jahanbakhsh, S., Nelson, A., Ray, D., Scott, D.D., Hennefarth, M., Moutal, A., Perez-Miller, S., Ambrose, A.J., Al-Shamari, A., Coursodon, P., Meechoovet, B., Reiman, R., Lyons, E., Beilstein, M., Chapman, E., Morris, Q.D., Van Keuren-Jensen, K., Hughes, T.R., Khanna, R., Koehler, C., Jen, J., Gokhale, V., Khanna, M. (2018) A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). ACS Chemical Biology. 13(10):3000-3010
- Wan, J., Yourshaw, M., Mamsa, H., Rudnik-Schöneborn, S., Menezes, M.P., Hong, J.E., Leong, D.W., Senderek, J., Salman, M.S., Chitayat, D., Seeman, P., von Moers, A., Graul-Neumann, L., Kornberg, A.J., Castro-Gago, M., Sobrido, M.J., Sanefuji, M., Shieh, P.B., Salamon, N., Kim, R.C., Vinters, H.V., Chen, Z., Zerres, K., Ryan, M.M., Nelson, S.F., and Jen, J.C. (2012) Mutations in the RNA exosome component gene EXOSC3 cause pontocerebellar hypoplasia and spinal motor neuron degeneration. Nature Genetics. 44(6):704-708
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