ZFIN ID: ZDB-FISH-150901-25831
Fish name: col1a1adc124/+
Genotype: col1a1adc124/+
Targeting Reagent: none
HUMAN DISEASE MODELED by col1a1adc124/+
Human Disease Conditions Citations
osteogenesis imperfecta type 3 standard conditions Gistelinck et al., 2018
osteogenesis imperfecta standard conditions (2)
GENE EXPRESSION
Gene expression in col1a1adc124/+
RNA expression No data available
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in col1a1adc124/+
Phenotype Conditions Figures
actinotrichium absent, abnormal physical alteration: anatomical structure Fig. 7 with image from Durán et al., 2011
actinotrichium decreased amount, abnormal standard conditions Fig. 7 with image from Durán et al., 2011
actinotrichium malformed, abnormal standard conditions Fig. 7 with image from Durán et al., 2011
bone mineralization disrupted, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Gioia et al., 2017
bone tissue collagen type I trimer physical quality, abnormal standard conditions Fig. 3 with image from Gioia et al., 2017
caudal fin morphology, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Gioia et al., 2017
caudal fin morphology, ameliorated chemical treatment by environment: sodium phenylbutyrate Fig. 4 from Gioia et al., 2017
centrum decreased volume, abnormal standard conditions Fig. 2 from Gistelinck et al., 2018
centrum ossification delayed, abnormal standard conditions Fig. 2 with image from Gioia et al., 2017
fin decreased size, abnormal standard conditions Fig. 7 with image from Durán et al., 2011
head flattened, abnormal standard conditions Fig. 1 with image from Gioia et al., 2017
lepidotrichium increased thickness, abnormal standard conditions Fig. 7 with image from Durán et al., 2011
lepidotrichium malformed, abnormal physical alteration: anatomical structure Fig. 7 with image from Durán et al., 2011
neural arch decreased volume, abnormal standard conditions Fig. 2 from Gistelinck et al., 2018
neural spine sloped, abnormal standard conditions Fig. 1 with image from Gioia et al., 2017
neural spine sloped, ameliorated chemical treatment by environment: sodium phenylbutyrate Fig. 4 from Gioia et al., 2017
osteoblast increased accumulation rib, abnormal standard conditions Table 2 from Gistelinck et al., 2018
osteoblast endoplasmic reticulum lumen increased size, abnormal standard conditions Fig. 3 with image from Gioia et al., 2017
osteoblast endoplasmic reticulum lumen size, ameliorated chemical treatment by environment: sodium phenylbutyrate Fig. 5 with image from Gioia et al., 2017
pelvic fin atrophied, abnormal standard conditions Fig. 1 with image from Gioia et al., 2017
pelvic fin kinked, abnormal standard conditions Fig. 1 with image from Gioia et al., 2017
rib deformed, abnormal standard conditions Fig. 1 with image from Gioia et al., 2017
spinal cord curved, abnormal standard conditions Table 2 from Gistelinck et al., 2018
vertebra fused with vertebra, abnormal standard conditions Table 2 from Gistelinck et al., 2018
Fig. 1 with image from Gioia et al., 2017
whole organism decreased length, abnormal standard conditions Fig. 1 with imageTable 2 from Gistelinck et al., 2018
Fig. 1 with image from Gioia et al., 2017

CITATIONS  (6)