ZFIN ID: ZDB-FISH-150901-25641
Fish name: ml2Tg
Genotype: ml2Tg
Targeting Reagent: none
HUMAN DISEASE MODELED by ml2Tg
Human Disease Conditions Citations
spinal muscular atrophy chemical treatment by environment: PYR-41 Oprişoreanu et al., 2021
GENE EXPRESSION
Gene expression in ml2Tg
RNA expression
Expressed Gene Structure Conditions Figures
ache standard conditions Figure 2 with image from Rima et al., 2020
alcama control Fig. 5 with image from Jao et al., 2012
calca standard conditions Fig. 4 from Zhong et al., 2012
chata physical alteration: anatomical structure Fig. 4 from Reimer et al., 2008
chodl standard conditions Fig. 4 from Zhong et al., 2012
chrna3 standard conditions Figure 2 with image from Rima et al., 2020
chrna7a standard conditions Figure 2 with image from Rima et al., 2020
col15a1b standard conditions Fig. 5 from Guillon et al., 2016
dcc standard conditions Fig. 8 from Rosenberg et al., 2014
Fig. 5 with image from Lim et al., 2011
transection: axon: neuron Fig. 8 from Rosenberg et al., 2014
fignl1 control Fig. 2 with image from Fassier et al., 2018
gjd2b standard conditions Fig. 3 from Carlisle et al., 2014
isl1a standard conditions Fig. 8 with image from Moreno et al., 2018
isl2a standard conditions Fig. 8 with image from Moreno et al., 2018
isl2b standard conditions Fig. 8 with image from Moreno et al., 2018
mc4r standard conditions Fig. 1 with image from Reinoß et al., 2020
mnx1 standard conditions Figure 1 with image from Gong et al., 2020
Fig. 1 with image from Reinoß et al., 2020
ncaldb control Fig. 3 from Riessland et al., 2017
nkx1.2lb standard conditions Fig. 3 from Zhong et al., 2012
nxph1 control Fig. 4 with image from Thomas-Jinu et al., 2013
plxna3 standard conditions Fig. 2 from Feldner et al., 2007
si:ch73-1a9.3 standard conditions Fig. 7 from Gao et al., 2019
slc5a7a standard conditions Figure 2 with image from Rima et al., 2020
smn1 control Fig. 3 from Riessland et al., 2017
sox2 standard conditions Figure 1 with image from Gong et al., 2020
sst1.1 standard conditions Fig. 5 with image from Djenoune et al., 2017
tac1 standard conditions Fig. 4 from Zhong et al., 2012
vsx2 standard conditions Fig. 1 with image from Reinoß et al., 2020
Fig. 3 from Zhong et al., 2012
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab1-chrna chemical treatment by environment: dipyridamole Fig. 4. with imageFig. 5. with image from Oprişoreanu et al., 2021
Ab1-chrna control Fig. 4. with imageFig. 5. with image from Oprişoreanu et al., 2021
znp-1 standard conditions Fig. 4. with imageFig. 5. with image from Oprişoreanu et al., 2021
Fig. 5 with image from Gribble et al., 2018
Fig. 3 from Riessland et al., 2017
Fig. 1Fig. 9 from Fox et al., 2007
zn-12 standard conditions Fig. 2 with image from Moreno et al., 2014
Ab1-mnx1 standard conditions Fig. 2 from Zhong et al., 2012
Ab3-ins standard conditions Fig. 1 with image from Arkhipova et al., 2012
Ab2-isl standard conditions Fig. 9 with image from Moreno et al., 2018
Fig. 1 with image from Arkhipova et al., 2012
znp-1 chemical treatment by environment: dipyridamole Fig. 4. with imageFig. 5. with image from Oprişoreanu et al., 2021
Ab1-GABA standard conditions Fig. 3 from Zhong et al., 2012
Ab1-chat standard conditions Fig. 2 from Zhong et al., 2012
Ab1-pax2 standard conditions Fig. 3 from Zhong et al., 2012
Ab3-sst standard conditions Fig. 1 with image from Arkhipova et al., 2012
Ab2-gcg standard conditions Fig. 1 with image from Arkhipova et al., 2012
Ab2-tuba control Fig. 2 with image from Fassier et al., 2018
Ab-SV2 standard conditions Fig. 9 from Fox et al., 2007
Ab1-isl standard conditions Fig. 2Fig. 3 from Zhong et al., 2012
Fig. S2 from Reimer et al., 2008
Ab1-synapsin standard conditions Fig. 1 from Fox et al., 2007
zn-8 alcama control Fig. 5 with image from Jao et al., 2012
Ab1-chat chata physical alteration: anatomical structure Fig. 4 from Reimer et al., 2008
Ab1-col15a1b col15a1b standard conditions Fig. 5 from Guillon et al., 2016
Ab1-fignl1 fignl1 control Fig. 2 with image from Fassier et al., 2018
Ab3-GFP GFP standard conditions Fig. 1 with image from Arkhipova et al., 2012
Ab1-ncald ncaldb control Fig. 3 from Riessland et al., 2017
Ab3-smn1 smn1 control Fig. 3 from Riessland et al., 2017
PHENOTYPE
Phenotype in ml2Tg
Phenotype Conditions Figures
CaP motoneuron axon branchiness, ameliorated chemical treatment by environment: dipyridamole, chemical treatment by environment: PYR-41 Fig. 6. with image from Oprişoreanu et al., 2021
CaP motoneuron axon increased branchiness, abnormal chemical treatment by environment: PYR-41 Fig. 6. with image from Oprişoreanu et al., 2021
CaP motoneuron axon extension decreased process quality, abnormal chemical treatment by environment: PYR-41 Fig. 6. with image from Oprişoreanu et al., 2021
CaP motoneuron axon extension process quality, ameliorated chemical treatment by environment: dipyridamole, chemical treatment by environment: PYR-41 Fig. 6. with image from Oprişoreanu et al., 2021
CaP motoneuron collateral sprouting increased occurrence, abnormal chemical treatment by environment: PYR-41 Fig. 6. with image from Oprişoreanu et al., 2021
CaP motoneuron collateral sprouting process quality, ameliorated chemical treatment by environment: dipyridamole, chemical treatment by environment: PYR-41 Fig. 6. with image from Oprişoreanu et al., 2021
motor neuron dead, abnormal chemical treatment by environment: bisphenol A Fig. S4 from Morrice et al., 2018
motor neuron decreased amount, abnormal chemical treatment: LY 364947 Fig. 7 with image from Casari et al., 2014
motor neuron axon decreased length, abnormal chemical treatment by environment: bisphenol A Fig. S3 from Morrice et al., 2018
pancreas decreased size, abnormal chemical treatment by environment: PK-11195, chemical treatment by environment: 4-hydroxynon-2-enal Fig. 9 with image from Lou et al., 2020
pancreas decreased size, abnormal chemical treatment by environment: 4-hydroxynon-2-enal Fig. 9 with image from Lou et al., 2020
pancreas decreased size, abnormal chemical treatment by environment: 3-allyl-2-[2-(diethylamino)ethoxy]benzaldehyde Fig. 5 with image from Lou et al., 2020
pancreas size, ameliorated chemical treatment by environment: carnosine, chemical treatment by environment: 4-hydroxynon-2-enal Fig. 9 with image from Lou et al., 2020
primary islet pancreatic B cell GFP expression increased distribution, abnormal chemical treatment by environment: hydrogen peroxide Fig. S5 from Ahmed Alfar et al., 2017
skeletal muscle apoptotic process increased occurrence, abnormal chemical treatment by environment: bisphenol A Fig. S7 with image from Morrice et al., 2018
spinal cord apoptotic process increased occurrence, abnormal chemical treatment by environment: bisphenol A Fig. S7 with image from Morrice et al., 2018

CITATIONS  (83)