ZFIN Fish: nns1Tg

ZFIN ID: ZDB-FISH-150901-14811

Fish name:	nns1Tg
Genotype:	nns1Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by nns1Tg
No data available

GENE EXPRESSION
Gene expression in nns1Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
isl1a	neuron	standard conditions	Fig. 3 from Kimura et al., 2006
lhx3	neuron	standard conditions	Fig. 3 from Kimura et al., 2006
nkx6.1	neuron	standard conditions	Fig. 3 from Kimura et al., 2006
sox2	retinal inner nuclear layer Muller cell	standard conditions	Fig. 1 from Vitorino et al., 2009
vsx2	spinal cord interneuron	standard conditions	Fig. 2 from Kimura et al., 2006

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-sox2	sox2	retinal inner nuclear layer Muller cell	standard conditions	Fig. 1 from Vitorino et al., 2009

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	CiD ciliary marginal zone eye optic cup optic vesicle retinal inner nuclear layer retinal bipolar neuron retinal outer nuclear layer spinal cord neural tube neuron	standard conditions	Fig. 2, Fig. 3 from Wycliffe et al., 2020 Fig. 7 from Seredick et al., 2014 Fig. 2 from Bräutigam et al., 2011 Fig. 1 from Vitorino et al., 2009

PHENOTYPE
Phenotype in nns1Tg

Phenotype	Conditions	Figures
spinal cord interneuron decreased amount, abnormal	chemical treatment by environment: Ginkgotoxin	Fig. 6 from Lee et al., 2012
spinal cord interneuron glutamatergic neuron decreased amount, abnormal	chemical treatment by environment: strychnine	Fig. 1 from Côté et al., 2012

CITATIONS (20)