ZFIN ID: ZDB-FISH-150901-1421
Fish name: ump2Tg
Genotype: ump2Tg
Targeting Reagent: none
HUMAN DISEASE MODELED by ump2Tg
Human Disease Conditions Citations
bacterial infectious disease bacterial treatment by injection: Mycobacterium marinum Johansen et al., 2020
bacterial treatment by injection: Mycobacteroides abscessus Santucci et al., 2019
GENE EXPRESSION
Gene expression in ump2Tg
Protein expression No data available
PHENOTYPE
Phenotype in ump2Tg
Phenotype Conditions Figures
blastema cell population proliferation decreased occurrence, abnormal chemical treatment by injection: clondronate(2-), chemical ablation: macrophage, amputation: caudal fin Fig. 2 with image from Nguyen-Chi et al., 2017
fin regeneration decreased efficacy, abnormal chemical treatment by injection: clondronate(2-), chemical ablation: macrophage, amputation: caudal fin Fig. 2 with image from Nguyen-Chi et al., 2017
macrophage mCherry expression absent, abnormal chemical treatment by injection: clondronate(2-), chemical ablation: macrophage Fig. 5 from Bernut et al., 2015
macrophage absent, abnormal bacterial treatment by injection: Burkholderia cenocepacia Fig. 1 with image from Mesureur et al., 2017
macrophage mCherry expression absent, abnormal bacterial treatment by injection: Burkholderia cenocepacia Fig. 1 with image from Mesureur et al., 2017
macrophage absent, abnormal chemical treatment by injection: clondronate(2-), chemical ablation: macrophage Fig. 5 from Bernut et al., 2015
macrophage dead, abnormal bacterial treatment by injection: Burkholderia cenocepacia Fig. 3 with image from Mesureur et al., 2017
macrophage decreased amount, abnormal bacterial treatment by injection: Burkholderia cenocepacia Fig. 1 with imageFig. 3 with image from Mesureur et al., 2017
macrophage decreased amount, abnormal chemical treatment by injection: clondronate(2-), chemical ablation: macrophage, amputation: caudal fin Fig. 2 with image from Nguyen-Chi et al., 2017
macrophage cxcl11.1 expression increased amount, abnormal bacterial treatment by injection: Mycobacterium marinum Figure 6 with image from Rougeot et al., 2019
macrophage activation increased occurrence, abnormal bacterial treatment by injection: Mycobacteroides abscessus Fig. 6 from Bernut et al., 2015
regenerating fin decreased length, abnormal chemical treatment by injection: clondronate(2-), chemical ablation: macrophage, amputation: caudal fin Fig. 2 with image from Nguyen-Chi et al., 2017
whole organism decreased life span, abnormal bacterial treatment by injection: Mycobacteroides abscessus Figure 4 with image from Santucci et al., 2019
whole organism decreased life span, exacerbated bacterial treatment by injection: Mycobacteroides abscessus, chemical treatment by injection: clondronate(2-), chemical ablation: macrophage Fig. 5 from Bernut et al., 2015
whole organism granuloma formation increased occurrence, abnormal bacterial treatment by injection: Mycobacteroides abscessus Figure 5 with image from Santucci et al., 2019

CITATIONS  (19)