ZFIN Fish: npas4l^Df(Chr13:lycat)m39/m39

ZFIN ID: ZDB-FISH-150901-11230

ZFIN ID: ZDB-FISH-150901-11230

Fish name:	npas4l^{Df(Chr13:lycat)m39/m39}
Genotype:	npas4l^{Df(Chr13:lycat)m39/m39}
Targeting Reagent:	none

HUMAN DISEASE MODELED by npas4l^{Df(Chr13:lycat)m39/m39}
No data available

GENE EXPRESSION
Gene expression in npas4l^{Df(Chr13:lycat)m39/m39}

RNA expression

Expressed Gene	Structure	Conditions	Figures
bif1.1	(not) posterior lateral plate mesoderm	standard conditions	Fig. 1 from Ghersi et al., 2019
bif1.2	posterior lateral plate mesoderm	standard conditions	Fig. S8 from Ghersi et al., 2019
cryaa	whole organism	control	Fig. 4 from Posner et al., 2019
cryaba	whole organism	control	Fig. 4 from Posner et al., 2019
cryabb	whole organism	control	Fig. 4 from Posner et al., 2019
etsrp	intermediate cell mass of mesoderm (not) lateral plate mesoderm	standard conditions	Fig. S4 from Reischauer et al., 2016 Fig. 6 from Li et al., 2014
fgf10a	mesenchyme pancreatic system mesenchyme	standard conditions	Fig. 6 from Wilfinger et al., 2013
fgf24	mesenchyme pancreatic system mesenchyme	standard conditions	Fig. 6 from Wilfinger et al., 2013
fli1	blood vasculature	standard conditions	Fig. 1 from Xiong et al., 2008
gata1a	(not) blood island intermediate cell mass of mesoderm	standard conditions	Fig. 1 from Mahony et al., 2016 Fig. S4 from Reischauer et al., 2016 Fig. 6 from Oates et al., 1999
gc	liver	standard conditions	Fig. 4 from Noël et al., 2010
hbae1.1	intermediate cell mass of mesoderm	control	Fig. 6 from Oates et al., 1999
hbbe3	intermediate cell mass of mesoderm	control	Fig. 6 from Oates et al., 1999
jak2a	(not) hematopoietic system (not) intermediate cell mass of mesoderm	control	Fig. 6, Table 1 from Oates et al., 1999
kdrl	(not) endothelial cell	control	Fig. 7 from Craig et al., 2015
lcp1	(not) regenerating fin	amputation	Fig. 5 from Yoshinari et al., 2009
ltbp3	bulbus arteriosus	standard conditions	Fig. S3 from Zhou et al., 2011
meis3	mesenchyme pancreatic system mesenchyme	standard conditions	Fig. 6 from Wilfinger et al., 2013
mmp9	regenerating fin	amputation	Fig. 5 from Yoshinari et al., 2009
mpx	(not) regenerating fin	amputation	Fig. 5 from Yoshinari et al., 2009
nfatc1	(not) endocardium olfactory placode	standard conditions	Fig. 1 from Wong et al., 2012
oxt	neurohypophysis axon terminus neurosecretory neuron axon terminus	standard conditions	Fig. 5 from Gutnick et al., 2011
pku300	whole organism	standard conditions	Fig. 2 from Wang et al., 2013
ren	(not) anterior mesenteric artery embryonic structure	standard conditions	Fig. 6 from Rider et al., 2015
sox7	(not) blood vessel endothelial cell rhombomere	standard conditions	Fig. S2 from Herpers et al., 2008
sox18	(not) blood vessel endothelial cell immature eye	standard conditions	Fig. S2 from Herpers et al., 2008
tal1	intermediate cell mass of mesoderm (not) lateral plate mesoderm	standard conditions	Fig. S4 from Reischauer et al., 2016 Fig. 6 from Li et al., 2014 Fig. 6, Fig. 7 from Oates et al., 1999
tbxta	notochord	standard conditions	Fig. S1 from Novikov et al., 2013
tfec	(not) blood island neural crest	standard conditions	Fig. 1 from Mahony et al., 2016
tmem88a	anterior lateral plate mesoderm (not) posterior lateral plate mesoderm	standard conditions	Fig. S1 from Novikov et al., 2013

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab2-oxt	oxt	neurohypophysis axon terminus neurosecretory neuron axon terminus	standard conditions	Fig. 5 from Gutnick et al., 2011

Reporter gene expression No data available

PHENOTYPE
Phenotype in npas4l^{Df(Chr13:lycat)m39/m39}

Phenotype	Conditions	Figures
anterior mesenteric artery ren expression absent, abnormal	standard conditions	Fig. 6 from Rider et al., 2015
anterior mesenteric artery ren expression decreased amount, abnormal	standard conditions	Fig. 6 from Rider et al., 2015
blood circulation arrested, abnormal	standard conditions	Fig. 6 from Rider et al., 2015
blood island tfec expression absent, abnormal	standard conditions	Fig. 1 from Mahony et al., 2016
blood island gata1a expression absent, abnormal	standard conditions	Fig. 1 from Mahony et al., 2016
blood vasculature morphology, abnormal	standard conditions	Fig. S2 from Herpers et al., 2008
blood vessel morphogenesis disrupted, abnormal	standard conditions	Fig. S2 from Herpers et al., 2008
cellular senescence magnitude, normal	standard conditions	Fig. 3 from Kishi et al., 2008
endocardium development disrupted, abnormal	standard conditions	Fig. 1 from Wong et al., 2012
eye decreased size, abnormal	standard conditions	Fig. 1 from Posner et al., 2019
eye lens opaque, abnormal	standard conditions	Fig. 1 from Zou et al., 2015
fin regeneration occurrence, normal	standard conditions	Fig. 6 from Yoshinari et al., 2009
heart shape, abnormal	standard conditions	Fig. 1 from Posner et al., 2019
hematopoietic system jak2a expression absent, abnormal	control	Table 1 from Oates et al., 1999
intermediate cell mass of mesoderm jak2a expression absent, abnormal	control	Fig. 6 from Oates et al., 1999
intermediate cell mass of mesoderm etsrp expression decreased amount, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016
intermediate cell mass of mesoderm hbae1.1 expression decreased amount, abnormal	control	Fig. 6 from Oates et al., 1999
intermediate cell mass of mesoderm gata1a expression decreased amount, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016 Fig. 6 from Oates et al., 1999
intermediate cell mass of mesoderm hbbe3 expression decreased amount, abnormal	control	Fig. 6 from Oates et al., 1999
intermediate cell mass of mesoderm tal1 expression decreased amount, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016 Fig. 6, Fig. 7 from Oates et al., 1999
intermediate cell mass of mesoderm gata1a expression decreased distribution, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016
intermediate cell mass of mesoderm etsrp expression decreased distribution, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016
intermediate cell mass of mesoderm tal1 expression decreased distribution, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016
intermediate cell mass of mesoderm decreased size, abnormal	standard conditions	Fig. S4 from Reischauer et al., 2016
lateral plate mesoderm tal1 expression absent, abnormal	control	Fig. 7 from Oates et al., 1999
lens decreased diameter, abnormal	standard conditions	Fig. 2 from Posner et al., 2019
lens enucleation decreased occurrence, abnormal	standard conditions	Fig. 6 from Wu et al., 2016
lens fiber cell nucleus increased amount, abnormal	standard conditions	Fig. 3 from Posner et al., 2019
neurohypophysis has normal numbers of parts of type neurosecretory neuron axon terminus, normal	standard conditions	Fig. 5 from Gutnick et al., 2011
neurohypophysis lacks all parts of type blood vasculature, abnormal	standard conditions	Fig. 5 from Gutnick et al., 2011
nucleate erythrocyte absent, abnormal	standard conditions	Fig. 1 from Posner et al., 2019
pericardium edematous, abnormal	standard conditions	Fig. 1 from Posner et al., 2019 Fig. 6 from Rider et al., 2015 Fig. S2 from Herpers et al., 2008
peritoneum edematous, abnormal	standard conditions	Fig. 6 from Rider et al., 2015
posterior lateral plate mesoderm bif1.1 expression absent, abnormal	standard conditions	Fig. 1 from Ghersi et al., 2019
posterior lateral plate mesoderm bif1.2 expression decreased amount, abnormal	standard conditions	Fig. S8 from Ghersi et al., 2019
posterior lateral plate mesoderm physical object quality, abnormal	standard conditions	Fig. S1 from Novikov et al., 2013
trunk bent, abnormal	standard conditions	Fig. 1 from Posner et al., 2019
whole organism lacks all parts of type endothelial cell, abnormal	standard conditions	Fig. S3 from Zhou et al., 2011

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