Engineered Region
SCP
- ID
- ZDB-EREGION-130214-2
- Name
- SCP
- Symbol
- SCP
- Previous Names
-
- Super Core Promoter (1)
- Location
- Unmapped
- Note
-
SCP contains four core promoter motifs-the TATA box initiator (Inr), motif ten element (MTE) and downstream promoter element (DPE)- in a single promoter, and is distinctly stronger than the cytomegalovirus (CMV) IE1 and adenovirus major late (AdML) core promoters both in vitro and in vivo. (Juven-Gershon, et al., 2006)
Constructs
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Et(ATTP-REX2-SCP1-Ocu.HBB2:Cre-2A-Cerulean-ATTP) |
| 8 | (5) | ||
| Et(hoxa2b-SCP1-Ocu.Hbb2:Cre-2A-Cerulean) |
|
| 1 | (2) | |
| Et(REX2-SCP1:GAL4FF) |
| 32 | (22) | ||
| Et(REX2-SCP1-Ocu.Hbb2:Cre) |
|
| 11 | (2) | |
| Et(REX2-SCP1-Ocu.HBB2:Cre-2A-Cerulean) |
|
| 10 | (6) | |
| Et(REX2-SCP1-Ocu.Hbb2:Cre-2A-Cerulean) |
|
| 32 | (3) | |
| Tg(ELTC-REX2-SCP1:Ocu.Hbb2-Cre-2A-Cerulean) |
| 1 | Tabor et al., 2018 | ||
| Tg(hoxb1a-SCP1:Ocu.Hbb2-Cre-2A-Cerulean) |
|
| 1 | Tabor et al., 2018 |
1 - 8 of 8
Show
Citations
- Tabor, K.M., Smith, T.S., Brown, M., Bergeron, S.A., Briggman, K.L., Burgess, H.A. (2018) Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit. Current biology : CB. 28(16):2527-2535.e8
- Bergeron, S.A., Hannan, M.C., Codore, H., Fero, K., Li, G.H., Moak, Z., Yokogawa, T., and Burgess, H.A. (2012) Brain selective transgene expression in zebrafish using an NRSE derived motif. Frontiers in neural circuits. 6:110
1 - 2 of 2
Show