Engineered Region

CAAX

ID
ZDB-EREGION-110816-11
Name
CAAX
Symbol
CAAX
Previous Names
None
Location
Unmapped
Note
This region targets proteins to the membrane. CAAX is the prenylation site recognized by farnesyltransferase and geranylgeranyltransferase. The CAAX box is located at the C-terminus of the protein. The identity of X determines which enzyme recognizes the site. The prenyl group is covalently bound to the cysteine. Proteins with an attached prenyl moity are membrane associated.
Constructs
Citations