Engineered Region
CAAX
- ID
- ZDB-EREGION-110816-11
- Name
- CAAX
- Symbol
- CAAX
- Previous Names
- None
- Location
- Unmapped
- Note
-
This region targets proteins to the membrane. CAAX is the prenylation site recognized by farnesyltransferase and geranylgeranyltransferase. The CAAX box is located at the C-terminus of the protein. The identity of X determines which enzyme recognizes the site. The prenyl group is covalently bound to the cysteine. Proteins with an attached prenyl moity are membrane associated.
Constructs
Citations