CRISPR

CRISPR3-keap1b

ID
ZDB-CRISPR-260105-2
Name
CRISPR3-keap1b
Previous Names
None
Target
Sequence
5' - TGTGCCCGCGCTGATGTTGG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "CGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf4245 keap1b
Expression
Gene expression in Wild Types + CRISPR3-keap1b
No data available
Phenotype
Phenotype resulting from CRISPR3-keap1b
No data available
Phenotype of all Fish created by or utilizing CRISPR3-keap1b
Phenotype Fish Conditions Figures
whole organism gstp1.2 expression increased amount, abnormal keap1bzf4245/zf4245 (AB) chemical treatment by environment: hydrogen peroxide Fig. 3 with image from Nguyen et al., 2025
whole organism viability, exacerbated keap1bzf4245/zf4245 (AB) chemical treatment by environment: copper(II) sulfate pentahydrate Fig. 4 with image from Nguyen et al., 2025
whole organism tnfb expression amount, ameliorated keap1bzf4245/zf4245 (AB) chemical treatment by environment: copper(II) sulfate pentahydrate Fig. 5 with image from Nguyen et al., 2025
response to oxidative stress process efficacy, ameliorated keap1bzf4245/zf4245 (AB) chemical treatment by environment: hydrogen peroxide Fig. 2 with image from Nguyen et al., 2025
whole organism gstp1.2 expression increased amount, abnormal keap1bzf4245/zf4245 (AB) standard conditions Fig. 3 with image from Nguyen et al., 2025
whole organism prdx1 expression increased amount, abnormal keap1bzf4245/zf4245 (AB) chemical treatment by environment: hydrogen peroxide Fig. 3 with image from Nguyen et al., 2025
inflammatory response decreased occurrence, abnormal keap1bzf4245/zf4245 (AB) standard conditions Fig. 5 with image from Nguyen et al., 2025
whole organism viability, ameliorated keap1bzf4245/zf4245 (AB) chemical treatment by environment: hydrogen peroxide Fig. 2 with image from Nguyen et al., 2025
whole organism prdx1 expression increased amount, abnormal keap1bzf4245/zf4245 (AB) standard conditions Fig. 3 with image from Nguyen et al., 2025
whole organism c3a.1 expression amount, ameliorated keap1bzf4245/zf4245 (AB) chemical treatment by environment: copper(II) sulfate pentahydrate Fig. 5 with image from Nguyen et al., 2025
Citations