CRISPR

CRISPR1-kcnd2

ID

ZDB-CRISPR-250128-64

Name

CRISPR1-kcnd2

Previous Names

None

Target

kcnd2 (1)

Sequence

5' - TGGTTCCTAAGACCATCATG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "GGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
chb22	kcnd2

Expression

Gene expression in Wild Types + CRISPR1-kcnd2

No data available

Phenotype

Phenotype resulting from CRISPR1-kcnd2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-kcnd2

Phenotype	Fish	Conditions	Figures
head col1a2 expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head atp2a1 expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head col11a1b expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
optic tectum neuronal action potential ictal, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 2 from LaCoursiere et al., 2024
regulation of trans-synaptic signaling decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head pde6ga expression decreased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head rps6kal expression decreased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
synaptic signaling decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
modulation of chemical synaptic transmission decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head usp6nl expression decreased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
trans-synaptic signaling decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head actc1b expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
anterograde trans-synaptic signaling decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head col5a1 expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head col1a1b expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head col11a1a expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head col5a2a expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
glutamate receptor signaling pathway decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head znf1124 expression decreased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
head slc4a1a expression increased amount, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
chemical synaptic transmission decreased process quality, abnormal	kcnd2^chb22/chb22	standard conditions	Fig. 4 from LaCoursiere et al., 2024
swimming behavior ictal, abnormal	kcnd2^chb22/+	chemical treatment by environment: pentetrazol	Fig. 1 from LaCoursiere et al., 2024

Citations