CRISPR

CRISPR2-mbnl1

ID

ZDB-CRISPR-220418-2

Name

CRISPR2-mbnl1

Previous Names

None

Target

mbnl1 (1)

Sequence

5' - ATGAATATGGCTCACATGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
b1359	mbnl1

Expression

Gene expression in Wild Types + CRISPR2-mbnl1

No data available

Phenotype

Phenotype resulting from CRISPR2-mbnl1

No data available

Phenotype of all Fish created by or utilizing CRISPR2-mbnl1

Phenotype	Fish	Conditions	Figures
heart alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359	standard conditions	Fig. 3. , Fig. 5. from Hinman et al., 2021
cornea alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
heart alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
swimming decreased occurrence, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 2. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
whole organism decreased length, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 1. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. , Fig. 5. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
cornea alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
whole organism decreased length, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 1. from Hinman et al., 2021
heart alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
swimming decreased occurrence, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 2. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. , Fig. 5. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
cornea alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359	standard conditions	Fig. 3. from Hinman et al., 2021
heart alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
swimming decreased occurrence, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 2. from Hinman et al., 2021
whole organism alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
brain alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
whole organism decreased length, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 1. from Hinman et al., 2021
skeletal muscle alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. , Fig. 5. from Hinman et al., 2021
cornea alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021
intestine alternative mRNA splicing, via spliceosome disrupted, abnormal	mbnl2^b1360/b1360; mbnl1^b1359/b1359; mbnl3^b1363/b1363	standard conditions	Fig. 3. from Hinman et al., 2021

Citations