CRISPR

CRISPR3-lrrk2

ID

ZDB-CRISPR-210414-3

Name

CRISPR3-lrrk2

Previous Names

None

Target

Sequence

5' - GGATAATCTGGCCAGACCGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sbu304	lrrk2

Expression

Gene expression in Wild Types + CRISPR3-lrrk2

No data available

Phenotype

Phenotype resulting from CRISPR3-lrrk2

No data available

Phenotype of all Fish created by or utilizing CRISPR3-lrrk2

Phenotype	Fish	Conditions	Figures
whole organism lef1 expression increased amount, abnormal	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020
whole organism sp5l expression increased amount, abnormal	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020
whole organism dkk1b expression increased amount, abnormal	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020
whole organism sp5a expression amount, ameliorated	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020
whole organism lef1 expression amount, ameliorated	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020
whole organism dkk1b expression amount, ameliorated	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020
whole organism sp5a expression increased amount, abnormal	lrrk2^{sbu304/sbu304}	chemical treatment by environment: 6-bromoindirubin-3'-oxime	Fig. 6 from Wint et al., 2020

Citations