CRISPR

CRISPR1-atp7b

ID
ZDB-CRISPR-210310-1
Name
CRISPR1-atp7b
Previous Names
None
Target
Sequence
5' - GAGACGGTTAAAGGGTTCC - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf3390 atp7b
zf3391 atp7b
Expression
Gene expression in Wild Types + CRISPR1-atp7b
No data available
Phenotype
Phenotype resulting from CRISPR1-atp7b
No data available
Phenotype of all Fish created by or utilizing CRISPR1-atp7b
Phenotype Fish Conditions Figures
male organism copper cation increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 7 from Mi et al., 2020
liver split, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism th expression increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 4 from Mi et al., 2020
male organism decreased thickness, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism epoa expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 6 from Mi et al., 2020
whole organism copper cation increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism pdgfba expression increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
liver fatty, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3,  Fig. 7 from Mi et al., 2020
brain th expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism slc6a3 expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism col1a1a expression increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism atp7b expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 1 from Mi et al., 2020
whole organism eno1a expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 6 from Mi et al., 2020
whole organism angpt2b expression amount, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 6 from Mi et al., 2020
female organism swimming decreased linear velocity, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
female organism decreased thickness, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism slc32a1 expression amount, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism gad1b expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 4 from Mi et al., 2020
whole organism hif1aa expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 6 from Mi et al., 2020
whole organism gad1b expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism th expression amount, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
male organism swimming decreased linear velocity, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism gabbr1a expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism gad2 expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism cidec expression increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3 from Mi et al., 2020
liver fatty, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate, chemical treatment by environment: roxadustat Fig. 7 from Mi et al., 2020
liver lipid increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3 from Mi et al., 2020
liver opaque, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3,  Fig. 7 from Mi et al., 2020
whole organism timp2b expression increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism pparg expression increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3 from Mi et al., 2020
liver fatty, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate, chemical treatment by environment: dimethyloxalylglycine Fig. 7 from Mi et al., 2020
whole organism tfa expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 6 from Mi et al., 2020
whole organism gad2 expression increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 4 from Mi et al., 2020
whole organism swimming behavior disrupted, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism fasn expression increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3 from Mi et al., 2020
brain slc6a3 expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
liver opacity, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate, chemical treatment by environment: dimethyloxalylglycine Fig. 7 from Mi et al., 2020
whole organism acaca expression decreased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 3 from Mi et al., 2020
liver fatty, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism copper cation increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 1 from Mi et al., 2020
whole organism swimming decreased linear velocity, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism acta2 expression increased amount, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
liver opacity, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate, chemical treatment by environment: roxadustat Fig. 7 from Mi et al., 2020
liver fibrotic, abnormal atp7bzf3390/zf3390 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism aldoaa expression amount, ameliorated atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 6 from Mi et al., 2020
whole organism morphology, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism acaca expression increased amount, abnormal atp7bzf3390/zf3390 (TU) chemical treatment by environment: copper(II) sulfate Fig. 3 from Mi et al., 2020
liver split, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
male organism decreased thickness, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism copper cation increased amount, abnormal atp7bzf3391/zf3391 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism col1a1a expression increased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism pdgfba expression increased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism atp7b expression decreased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 1 from Mi et al., 2020
male organism copper cation increased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 1 from Mi et al., 2020
female organism copper cation increased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 1 from Mi et al., 2020
female organism swimming decreased linear velocity, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
female organism decreased thickness, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism swimming behavior disrupted, abnormal atp7bzf3391/zf3391 (TU) chemical treatment by environment: copper(II) sulfate Fig. 4 from Mi et al., 2020
whole organism timp2b expression increased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
male organism swimming decreased linear velocity, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
liver fatty, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
whole organism acta2 expression increased amount, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
liver fibrotic, abnormal atp7bzf3391/zf3391 (TU) standard conditions Fig. 2 from Mi et al., 2020
Citations
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