CRISPR

CRISPR2-myl4

ID
ZDB-CRISPR-200708-4
Name
CRISPR2-myl4
Previous Names
None
Target
Sequence
5' - ATTTCTCTCACCCTCAGGTCTGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 3
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
bw24 myl4
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Expression
Gene expression in Wild Types + CRISPR2-myl4
No data available
Phenotype
Phenotype resulting from CRISPR2-myl4
No data available
Phenotype of all Fish created by or utilizing CRISPR2-myl4
Phenotype Fish Conditions Figures
heart myh6 expression increased amount, abnormal myl4bw24/bw24; bw6Tg standard conditions Fig. 2,  Fig. 4 from Ghazizadeh et al., 2019
heart action potential normal duration, ameliorated myl4bw24/bw24; bw6Tg chemical treatment by environment: CARBENOXOLONE Fig. 5 from Ghazizadeh et al., 2019
heart aldh1a2 expression increased amount, abnormal myl4bw24/bw24; bw6Tg standard conditions Fig. 2 from Ghazizadeh et al., 2019
heart calcium atom increased amount, abnormal myl4bw24/bw24; bw6Tg standard conditions Fig. 5 from Ghazizadeh et al., 2019
heart calcium atom normal amount, ameliorated myl4bw24/bw24; bw6Tg chemical treatment by environment: gap junctional intercellular communication inhibitor Fig. 5 from Ghazizadeh et al., 2019
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Citations
TSV
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