CRISPR
CRISPR1-vcp
- ID
- ZDB-CRISPR-190110-4
- Name
- CRISPR1-vcp
- Previous Names
-
- CROISPR1-vcp
- Target
- Sequence
-
5' - GAAGGTTCGCATGAACAGGG - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
- None
- Genome Resources
- None
Target Location
Constructs
No data available
Genomic Features
Expression
Gene expression in Wild Types + CRISPR1-vcp
No data available
Phenotype
Phenotype resulting from CRISPR1-vcp
No data available
Phenotype of all Fish created by or utilizing CRISPR1-vcp
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Citations
- Voisard, P., Diofano, F., Glazier, A.A., Rottbauer, W., Just, S. (2022) CRISPR/Cas9-Mediated Constitutive Loss of VCP (Valosin-Containing Protein) Impairs Proteostasis and Leads to Defective Striated Muscle Structure and Function In Vivo. International Journal of Molecular Sciences. 23(12)
- Kustermann, M., Manta, L., Paone, C., Kustermann, J., Lausser, L., Wiesner, C., Eichinger, L., Clemen, C.S., Schröder, R., Kestler, H.A., Sandri, M., Rottbauer, W., Just, S. (2018) Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo. Autophagy. 14(11):1911-1927
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