CRISPR

CRISPR2-esrp1

ID

ZDB-CRISPR-181219-1

Name

CRISPR2-esrp1

Previous Names

None

Target

esrp1 (1)

Sequence

5' - GGAGCAAGTGGGGATAAGTTGGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
crg1	esrp1

Expression

Gene expression in Wild Types + CRISPR2-esrp1

No data available

Phenotype

Phenotype resulting from CRISPR2-esrp1

No data available

Phenotype of all Fish created by or utilizing CRISPR2-esrp1

Phenotype	Fish	Conditions	Figures
whole organism esrp1 expression decreased amount, abnormal	esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
esophagus structure, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
whole organism Ab1-esrp1 labeling decreased amount, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
mRNA processing process quality, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 5, Fig. 6 from Burguera et al., 2017
swim bladder inflation decreased occurrence, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
inner ear decreased volume, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
mRNA splicing, via spliceosome process quality, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 5, Fig. 6 from Burguera et al., 2017
whole organism decreased life span, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	text only from Burguera et al., 2017
whole organism esrp2 expression decreased amount, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
whole organism Ab1-esrp2 labeling decreased amount, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
whole organism dead, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	text only from Burguera et al., 2017
whole organism esrp1 expression decreased amount, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
basibranchial position, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
pectoral fin morphology, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
esophagus decreased diameter, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
dorsolateral septum structure, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
mesethmoid bone morphology, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
swim bladder epithelium increased thickness, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
ethmoid cartilage split, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
pectoral fin endoskeletal disc malformed, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017
swim bladder epithelium decreased size, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. S3 from Burguera et al., 2017
olfactory epithelium morphology, abnormal	esrp2^crg2/crg2; esrp1^crg1/crg1	standard conditions	Fig. 1 from Burguera et al., 2017

Citations