CRISPR

CRISPR5-pax2a

ID
ZDB-CRISPR-180827-10
Name
CRISPR5-pax2a
Previous Names
None
Target
Sequence
5' - GGCGGTGTGAACCAGCTAGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
cu17 pax2a
Expression
Gene expression in Wild Types + CRISPR5-pax2a
No data available
Phenotype
Phenotype resulting from CRISPR5-pax2a
Phenotype Fish Figures
thyroid follicle aplastic/hypoplastic, abnormal ulb4Tg + CRISPR5-pax2a Fig. 3 with image from Trubiroha et al., 2018
Phenotype of all Fish created by or utilizing CRISPR5-pax2a
Phenotype Fish Conditions Figures
Muller cell morphology, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Table S4 from Charlton-Perkins et al., 2019
retinal outer plexiform layer morphology, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image from Charlton-Perkins et al., 2019
Muller cell physical object quality, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image,  Table S4 from Charlton-Perkins et al., 2019
Muller cell cell body displaced, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Table S4 from Charlton-Perkins et al., 2019
outer limiting membrane broken, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image,  Table S4 from Charlton-Perkins et al., 2019
Muller cell cell body position, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image from Charlton-Perkins et al., 2019
retina disorganized, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image from Charlton-Perkins et al., 2019
Muller cell glial cell projection overlap with Muller cell glial cell projection, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Table S4 from Charlton-Perkins et al., 2019
retinal inner plexiform layer morphology, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image,  Table S4 from Charlton-Perkins et al., 2019
Muller cell pax2a expression decreased amount, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure S4 with image from Charlton-Perkins et al., 2019
inner limiting membrane broken, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image,  Table S4 from Charlton-Perkins et al., 2019
Muller cell cell body spatial pattern, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Figure 4 with image from Charlton-Perkins et al., 2019
retinal inner plexiform layer decreased thickness, abnormal mi2001Tg + CRISPR5-pax2a + CRISPR6-pax2a standard conditions Table S4 from Charlton-Perkins et al., 2019
thyroid follicle aplastic/hypoplastic, abnormal ulb4Tg + CRISPR5-pax2a standard conditions Fig. 3 with image from Trubiroha et al., 2018
Muller cell pax2a expression absent, abnormal pax2acu17/cu17; mi2001Tg standard conditions Figure S4 with image from Charlton-Perkins et al., 2019
Citations
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