CRISPR

CRISPR7-myd88

ID

ZDB-CRISPR-180726-1

Name

CRISPR7-myd88

Previous Names

None

Target

Sequence

5' - GGCGGCAGACTGGAGGACAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
xt29	myd88

Expression

Gene expression in Wild Types + CRISPR7-myd88

No data available

Phenotype

Phenotype resulting from CRISPR7-myd88

No data available

Phenotype of all Fish created by or utilizing CRISPR7-myd88

Phenotype	Fish	Conditions	Figures
positive regulation of NF-kappaB transcription factor activity decreased magnitude, abnormal	nc1Tg + CRISPR7-myd88 + CRISPR8-myd88	chemical treatment by injection: lipopolysaccharide	Fig. 5 from Hsu et al., 2018
positive regulation of lipopolysaccharide-mediated signaling pathway decreased magnitude, abnormal	nc1Tg + CRISPR7-myd88 + CRISPR8-myd88	chemical treatment by injection: lipopolysaccharide	Fig. 5 from Hsu et al., 2018
positive regulation of NF-kappaB transcription factor activity decreased magnitude, abnormal	nc1Tg + CRISPR7-myd88 + CRISPR8-myd88	standard conditions	Fig. 5 from Hsu et al., 2018
angiogenesis increased occurrence, abnormal	myd88^xt29/xt29; s843Tg	chemical treatment by injection: trehalose 6,6'-dimycolate	Fig. S3 from Walton et al., 2018
neutrophil chemotaxis process efficacy, ameliorated	mir223^pu18/pu18 + CRISPR7-myd88 + CRISPR8-myd88	transection: caudal fin	Fig. 3 from Zhou et al., 2018
caudal fin neutrophil increased amount, ameliorated	mir223^pu18/pu18 + CRISPR7-myd88 + CRISPR8-myd88	transection: caudal fin	Fig. 3 from Zhou et al., 2018

Citations