CRISPR

CRISPR1-esf1

ID
ZDB-CRISPR-180327-2
Name
CRISPR1-esf1
Previous Names
None
Target
Sequence
5' - GGAGTGTGACTCTGCTGAAA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ouc3 esf1
ouc4 esf1
ouc5 esf1
Expression
Gene expression in Wild Types + CRISPR1-esf1
No data available
Phenotype
Phenotype resulting from CRISPR1-esf1
No data available
Phenotype of all Fish created by or utilizing CRISPR1-esf1
Phenotype Fish Conditions Figures
pharyngeal arch vgll2a expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
whole organism mdm2 expression increased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
midbrain hindbrain boundary decreased thickness, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
cranial neural crest sox10 expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6,  Fig. 7 from Chen et al., 2018
brain necrotic, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
intestinal bulb morphology, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
rRNA processing disrupted, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 8 from Chen et al., 2018
whole organism cytosolic small ribosomal subunit decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 8 from Chen et al., 2018
pharyngeal arch dlx2a expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
head apoptotic process increased occurrence, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
pharyngeal arch nrp2b expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch sox9a expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch cartilage absent, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4,  Fig. 5,  Fig. 9 from Chen et al., 2018
pharyngeal arch necrotic, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
neurocranial trabecula malformed, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
head cell population proliferation decreased occurrence, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
head decreased size, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
migratory cranial neural crest dlx2a expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch migratory cranial neural crest sox10 expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 7 from Chen et al., 2018
swim bladder uninflated, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
fourth ventricle hydrocephalic, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
mandibular arch skeleton decreased size, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 5 from Chen et al., 2018
hindbrain morphology, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
migratory cranial neural crest sox10 expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6,  Fig. 7 from Chen et al., 2018
migratory cranial neural crest crestin expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
neurocranium dorsal region absent, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
cranial neural crest crestin expression decreased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 6 from Chen et al., 2018
swim bladder absent, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
optic fissure closure incomplete, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
mandibular arch skeleton malformed, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4,  Fig. 5 from Chen et al., 2018
pericardium edematous, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4,  Fig. 5 from Chen et al., 2018
eye decreased size, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
whole organism tp53 expression increased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
whole organism ccng1 expression increased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
head morphology, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
whole organism dead, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 4 from Chen et al., 2018
whole organism cdkn1a expression increased amount, abnormal esf1ouc3/ouc3 (TU) standard conditions Fig. 9 from Chen et al., 2018
pharyngeal arch vgll2a expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
midbrain hindbrain boundary decreased thickness, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
cranial neural crest sox10 expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
brain necrotic, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
intestinal bulb morphology, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
pharyngeal arch dlx2a expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch nrp2b expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch sox9a expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch cartilage absent, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
pharyngeal arch necrotic, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
neurocranial trabecula malformed, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
head decreased size, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
migratory cranial neural crest dlx2a expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
swim bladder uninflated, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
fourth ventricle hydrocephalic, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
hindbrain morphology, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
migratory cranial neural crest sox10 expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
migratory cranial neural crest crestin expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
neurocranium dorsal region absent, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
cranial neural crest crestin expression decreased amount, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 6 from Chen et al., 2018
swim bladder absent, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
optic fissure closure incomplete, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
mandibular arch skeleton malformed, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
pericardium edematous, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
eye decreased size, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
whole organism dead, abnormal esf1ouc4/ouc4 (TU) standard conditions Fig. 4 from Chen et al., 2018
midbrain hindbrain boundary decreased thickness, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
pharyngeal arch vgll2a expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
cranial neural crest sox10 expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
brain necrotic, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
intestinal bulb morphology, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
neurocranial trabecula malformed, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
pharyngeal arch dlx2a expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch nrp2b expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch sox9a expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch cartilage absent, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
pharyngeal arch necrotic, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
head decreased size, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
fourth ventricle hydrocephalic, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
migratory cranial neural crest dlx2a expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
swim bladder uninflated, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
migratory cranial neural crest sox10 expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
migratory cranial neural crest crestin expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
mandibular arch skeleton malformed, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
cranial neural crest crestin expression decreased amount, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 6 from Chen et al., 2018
neurocranium dorsal region absent, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
pericardium edematous, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
optic fissure closure incomplete, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
eye decreased size, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
hindbrain morphology, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
whole organism dead, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
swim bladder absent, abnormal esf1ouc5/ouc5 (TU) standard conditions Fig. 4 from Chen et al., 2018
pharyngeal arch EGFP expression decreased amount, abnormal esf1ouc4/ouc4; y1Tg standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch EGFP expression decreased amount, abnormal esf1ouc5/ouc5; y1Tg standard conditions Fig. 6 from Chen et al., 2018
pharyngeal arch cartilage amount, ameliorated esf1ouc3/ouc3 + MO4-tp53 standard conditions Fig. 9 from Chen et al., 2018
head morphology, ameliorated esf1ouc3/ouc3 + MO4-tp53 standard conditions Fig. 9 from Chen et al., 2018
Citations
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