CRISPR

CRISPR2-ttn.2

ID

ZDB-CRISPR-160224-2

Name

CRISPR2-ttn.2

Previous Names

CRISPR2-ttna

Target

ttn.2 (1)

Sequence

5' - GACTACAAATTTGTGGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sfc9	ttn.2

Expression

Gene expression in Wild Types + CRISPR2-ttn.2

No data available

Phenotype

Phenotype resulting from CRISPR2-ttn.2

No data available

Phenotype of all Fish created by or utilizing CRISPR2-ttn.2

Phenotype	Fish	Conditions	Figures
atrium sarcomere morphology, abnormal	ttn.2^sfc9/sfc9	standard conditions	Fig. S11 from Ahlberg et al., 2018
atrium ab1-actn labeling spatial pattern, abnormal	ttn.2^sfc9/sfc9	standard conditions	Fig. S11 from Ahlberg et al., 2018
atrium Z disc blurry, abnormal	ttn.2^sfc9/sfc9	standard conditions	Fig. S11 from Ahlberg et al., 2018
heart contraction decreased process quality, abnormal	ttn.2^sfc9/sfc9 (EKW)	standard conditions	text only from Zou et al., 2015
cardiac muscle sarcomere disorganized, abnormal	ttn.2^sfc9/sfc9 (EKW)	standard conditions	Fig. 2 from Zou et al., 2015
heart functionality, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 3 , Table 5 from Ahlberg et al., 2018
atrium sarcomere decreased length, abnormal	ttn.2^sfc9/+	standard conditions	Fig. S13 from Ahlberg et al., 2018
atrium Z disc blurry, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 2 , Fig. S12 from Ahlberg et al., 2018
cardiac conduction irregular rhythm, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 3 from Ahlberg et al., 2018
cardiac ventricle M band absent, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 2 from Ahlberg et al., 2018
cardiac ventricle sarcomere increased width, abnormal	ttn.2^sfc9/+	standard conditions	Fig. S13 from Ahlberg et al., 2018
atrium sarcomere disorganized, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 2 , Fig. S12 from Ahlberg et al., 2018
cardiac ventricle I band absent, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 2 , Fig. S12 from Ahlberg et al., 2018
cardiac ventricle sarcomere decreased length, abnormal	ttn.2^sfc9/+	standard conditions	Fig. S13 from Ahlberg et al., 2018
atrium sarcomere increased width, abnormal	ttn.2^sfc9/+	standard conditions	Fig. S13 from Ahlberg et al., 2018
atrium morphology, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 3 from Ahlberg et al., 2018
cardiac ventricle Z disc increased thickness, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 2 from Ahlberg et al., 2018
atrium I band absent, abnormal	ttn.2^sfc9/+	standard conditions	Fig. 2 from Ahlberg et al., 2018

Citations