Genomic Feature
m245
- ID
- ZDB-ALT-980203-577
- Name
- m245
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Driever Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 16: 42509604 (GRCz11) (1) Details
- Nucleotide change
- T/G
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>C (1)
- Transcript Consequence
- Stop Loss (1)
- Protein Consequence
- Elongated Polypeptide: 29 AA added (1)
- Flanking Sequence
-
TGATAAGACCTCAGTGTGTTGTCAGGTACTATAGGTATTCATTTTGTTTTTACTCACTGTATTTTTTGAATTCTCAAAGTGCCTGTAGCCATGGACTGATTTTGTTAACCACCGAAAAGGCCTCTTTTTTGTTCTACAGAAGAAAGAAATGACCTAATTGGATAGGTTTTCATTTTTGAGGTGAACTGTCCCCTTTAGACGTGATGCATCATGGAAAATAAAAATCTGCAGTTGTCCAGTGTTGCGTTCAGCGATCTCCATCATTTGCTGTGAGATGAATCTTTAAAGGTAGCACAAAAACATCTGCAGTTCTCTTATCATCGCTAAAACTCATGCTCGAAGTCCCTTCACCTTTTTCTATTCTCCAGCACAACTGCGCGACGCAGCACGTCCAGGTCGTCCGGTACTGTTATTTACATTTCGTAAGCGTGTGTTTTTTTTGCGTGTGTGAATTCGCATGCCAGCGAAAGGTAAATGGTATCACTCTGCAGTGTCAGGAA
T/G CATACAAACGGGGTCATGACTGTTGAAGAGTGCCGCAGTCCCTGGATGGCGGCGTAGGGCCCTTGCTGGAAGTAGTGGTGGTAGCGCGGCATGTGGAAGGAGGGGAAGGTGGGTCCGGTGGCCTGCATGGAGCTGGCGAGGGCGGATGGAGTAAGGGGCATTCCCAGACGACTGTAGGGGGGGAGGGAGCCCTGGATGGGGTGCGGGAGAGGACTGGCCAGGGACGCCGTGCTGGTGCCGATGGCAGACAGAGACTGAGGGTGCTGAAAGCCAGAGAAACCAGATGTGGTGGTCACCCAAGAGCTGAGGGAGAGGTTGTCAGATGCAGTGAACGCTGAACCTGTACAGGAAAATAATGAATTATTGGTATTATAAAATTAGCATAGTTGCACCATAATATAAACAATGTTAGTATAGAAACAGAAGAAGGTACATAAAAAAAAAAGTTTAATAACATGCACTGTAAAAAATGATTTCATTTTAGTAATGAATAGGTTATT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| tbx20m245/m245 | Homozygous | ♀+/- ♂+/- | 3 figures  from Just et al., 2016 | Fig. 3 from Just et al., 2016 | |
| tbx20m245/m245 (AB) | Homozygous | ♀+/- ♂+/- | Table 2 from Stainier et al., 1996 | ||
| tbx20m245 (AB) | Unknown | Unknown | Fig. for (m245) from Phenotype Annotation (1994-2006) | ||
| tbx20m245/m245; s883Tg | Complex | Fig. 3 from Just et al., 2016 |
1 - 4 of 4
Show
Supplemental Information
- Genotyping protocol
- None
- Just, S., Raphel, L., Berger, I.M., Bühler, A., Keßler, M., Rottbauer, W. (2016) Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS One. 11:e0167306
- Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46
- Stainier, D.Y., Fouquet, B., Chen, J.N., Warren, K.S., Weinstein, B.M., Meiler, S.E., Mohideen, M.A., Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Driever, W., and Fishman, M.C. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123:285-292
1 - 3 of 3
Show