Genomic Feature
m233
- ID
- ZDB-ALT-980203-555
- Name
- m233
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation
- Protocol
- adult males treated with ENU
- Lab of Origin
- Driever Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 16: 39131540 (GRCz11) (1) Details
- Nucleotide change
- T/C
- Variant Notes
-
c.1A>G, pMet1Val
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>G at position 1 (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Met>Val at position 1 (1)
- Flanking Sequence
-
ACTTGCTTCACAAGTCTTTAAAGTTTGAGTTTAAGGCGTGAACACCATATTAAAATAATTATATAATTTAAGAATAACTTCTTTAAATAAAAAAGAAGAATAACTTTTAAGTGCAACAGTGCATGCTTCAAATAATGCATAAAACAGAATAAAGCAATACAAACCTTTTCCCTTGTCCACGAAACTCGTTATGGTGTTTGCAGACTTTGAAGAGCGGAAAAAGCTCGCATTGAGCCCCAGTTTCTCAGCGGCGGAGTAAGTCCTGTATATGGAGATCATGTAGTCATGAGGCACAACCGGGTCCTTAAAATCATCCCGACGACTCGCGCCCGGTGATGATGCTAAAATCTCTTTAAGAAATTTATGTGACCTTTGTCCATCAAACGCGCTCCTGGCACCCTTGCTCCTTTTCTGCGATATTAGCGCAGCTGACTGGCAACACGGTAAACTCCAGAGGAAAACGAAGAGCGCGTAAAAGGCGACTGCTCTCAAGGCATCCA
T/C GGTGTTACTATCCTCCAAAGAGTAAAGTGGAGCCGTGTCTCACAGTGAAGCCGGACTTTTTGGTTTGTGTTTGTTTGACGAGCGCGGACAGCGCGAGATCGGCGTGTTGCGTGTCTGAAGTGAAGTGCGCTGTAGACTCGAGAGCGCGAGGCTGCAGACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACTCACTCTCTCACATACACAAACTCACGTATACACACTCACTCGTGGCACGCCCACTGCACTCCTCAGACTATCCTGTATATATTGAACTTATCCACACTCTCTGCACAACTTTTCAGCTCAACAGCTCCTCAGCACATCATTTTAATATTCTCTAGATATATACTTATTATTAACAGTAAAACATTGCTTAGTAAGTGTTTAAATTGCATTTTACATATATACCTTTTTTAAATGTGTTATTATTGTTATTATGTTTTCATAATTTGTAGAACTAATGTCA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| gdf6am233/m233 (AB) | Homozygous | ♀+/- ♂+/- | 5 figures  from 2 publications | ||
| gdf6am233/+ (AB) | Heterozygous | Unknown | |||
| gdf6am233 (AB) | Unknown | Unknown | Fig. for (m233) from Phenotype Annotation (1994-2006) |
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Supplemental Information
- Genotyping protocol
- None
- den Hollander, A.I., Biyanwila, J., Kovach, P., Bardakjian, T., Traboulsi, E., Ragge, N.K., Schneider, A., and Malicki, J. (2010) Genetic defects of GDF6 in the zebrafish out of sight mutant and in human eye developmental anomalies. BMC Genetics. 11:102
- Malicki, J. (2000) Harnessing the power of forward genetics – analysis of neuronal diversity and patterning in the zebrafish retina. Trends in neurosciences. 23(11):531-541
- Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46
- Malicki, J., Neuhauss, S.C., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Abdelilah, S., Zwartkruis, F., Rangini, Z., and Driever, W. (1996) Mutations affecting development of the zebrafish retina. Development (Cambridge, England). 123:263-273
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