ZFIN ID: ZDB-ALT-980203-1333
Genomic Feature: tq253a
Synonyms: AQ53A (1), sunrise (1)
Affected Genomic Regions: pax6b
Type: Point Mutation (1)
Protocol: adult males treated with ENU
Lab Of Origin: Nüsslein-Volhard Lab
Location: Chr 7: 15889258 (GRCz11) (1) Details
Sequence:
Current Sources: European Zebrafish Resource Center (EZRC)    (order this)
MUTATION DETAILS
DNA/cDNA Change: T>C (1)
Transcript Consequence: Missense (1)
Protein Consequence: Amino Acid Substitution: Leu>Pro at position 244 (1)
FLANKING SEQUENCE (GENOMIC)
AAAGCGATGCTTGTTAGCATAGGTTAATGTGCTGTGAGTTAACAAGAACTAATAACAAATGACTGCATTTTTAAAAAAGATGAATAAATAGTGTACTAAATGTATTGTTTATTATGTGTTCATGATAGTAAATGCATTAACAATTATTAACTAATGGAGCTTTACTGTAAAGTGAGATGTAATAATAATAACACATAAAAAAAAACGGAAAAAATAAAGCAATCTAGTTGCCATTTATTTCTTTTTAACTTTTGTTTCAGATTTAAGTTAAACTAAAGTAACAATACCACATGCAACATGGTGTGAGAAGTCTGCCCGATCTTGCAACTATATATGTTATATTTTTGCAGACGGTTGCCAGCAACAGGACAACGGTGGTGAAAACACAAACTCCATCAGCTCAAACGGCGAGGACTCAGACGAGACTCAAATGCGTCTGCAGCTGAAAAGAAAACTGCAGAGAAACAGAACGTCCTTCACGCAGGAGCAGATCGAGGCAC
T/C
TGAGAAAGGTGAACGATCACAACTTTATTTGTATGTATACATAAATATATATATAACTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAACAGTTGAAGTCAGAATTATTAGCCCCCCTGTTCATTCGTTTAGTCTTTTTTAAATATTTGCCAAATGATGTTTAACAGAGCAAGGAAATTTTCACAGTATGTCTGATAATATTTTTTCTTCTGGAGAAAGTCTTATTTGTTTTATTTCGGCTAGAATAAAAGCAGTTTTGAATTTTTACAGAATCATTTTTAAGGTTCAAATTATTAGCCCCTTTAAGATATTTTTAAGATATATATTTGCTACGTTGTTTAAGTTTAAAATTTCTTTGGAATATAGCTAAATATACAGTTGAGATCAGATATTTAGCCCTTTAATGTGTAGTGTAGTGTTTCCATAATTATGGATGATATATTGGAGTGA
Comment Citation
The T to C change results in a L244P mutation in a highly conserved residue of  ... ZFIN Staff
OTHER tq253a PAGES No links to external sites
GENOTYPES
Zygosity Genotype (Background) Affected Genomic Regions Parental Zygosity
Homozygous pax6btq253a/tq253a pax6b ♀+/- ♂+/-
pax6btq253a/tq253a pax6b Unknown
pax6btq253a/tq253a pax6b ♀-/- ♂-/-
Unknown pax6btq253a pax6b Unknown

CITATIONS  (10)