Genomic Feature
cy52
- ID
- ZDB-ALT-201208-10
- Name
- cy52
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Epidermal Stem Cell Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 22: 24647224 - 24647225 (GRCz11) (1) Details
- Nucleotide change
- cA/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 2 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
ACAACAACAACAACAAAAAAAGTAAATAAAAAAATCTCACTCATAACGGTTGTGTGGAAAATTATTACGGTTTTAAAACCTTGACTTTATTGCCCTACGCCTAGCACTAGGGCACAAGTGAGTATTTTACTGAATTTGTTTTCATTTAGTCTGCTTACTTTCTGTCAGTCACATCATGTTTGTTATCTTCATCTCTGAATTATGGGTTTCCTTCTAAATGGCTCTCATGAATAACTAACTGAAGTGCTATAACTGAAACCCTTTAGACCCACACAATGCACTTATTTTGTTTGTTTTTTCTAGTCCTAGTGGGTTTTGTCCAAAGATGGCCAGGCACAACATCTGCTACCATGACCAGCCCATGGCCTTTTTCTACAACAACAGCAACATCACCTCAGATGAATGGGACCGCACACAGCTCATCCTGGTTCAGTGTGTTAGTTCAATCTGCTGTTGTTTCATCCTGGTAGCCAATGCCATGATCATAGCAGCGGTGGTGA
cA/- AACAAGAGGTTTCACTACCCTTTCTACTATCTCCTCGCCAACCTTGCCGCCTCAGACTTTCTCGCTGGAATCGCTTACATTTATCTCATGTTCAACACAGGGAAAATATCTCGTGATCTAACCGTTCAAGGCTACTTTTTTCGTCAGGGTTTGCTGGACGCGAGTCTTTCTGCATCTCTGACCAACCTCCTGGTGATCGCCCTGGAGCGCTACATCTCCATCTTGAACTTTAAGGTTCACAGTAACCTCACCAAGCGCAGAGTGACTCTGTTGATCGCCCTAGTATGGGGTATCTCCATATTCATGGGGGCCGTTCCTAGTTTGGGCTGGAACTGTATCTGCAGTCTGGATCTGTGCTCTAAATTGGCCCCCATCTTTAGCCGGAGCTACCTGATCTTCTGGTCTGTGTCCAACCTGGTGCTCTTCCTCATCATGGTGGGGGTCTATGTAAGGATTTACGTCTATGTGGTGAAAAAGACAGTTGTCCTGAAGGCGCACAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| lpar3cy52/cy52 | Homozygous | Unknown | Fig. 6 from Lin et al., 2017 | ||
| lpar3cy52/cy52 | Homozygous | ♀+/- ♂+/- | 8 figures  from 2 publications | Figure 5 from Chen et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Lin, Y.N., Audira, G., Malhotra, N., Ngoc Anh, N.T., Siregar, P., Lu, J.H., Lee, H., Hsiao, C.D. (2020) A Novel Function of the Lysophosphatidic Acid Receptor 3 (LPAR3) Gene in Zebrafish on Modulating Anxiety, Circadian Rhythm Locomotor Activity, and Short-Term Memory. International Journal of Molecular Sciences. 21(8):
- Chen, W.M., Chiang, J.C., Lin, Y.C., Lin, Y.N., Chuang, P.Y., Chang, Y.C., Chen, C.C., Wu, K.Y., Hsieh, J.C., Chen, S.K., Huang, W.P., Chen, B.P.C., Lee, H. (2019) Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome. Aging Cell. 19(1):e13064
- Lin, K.H., Li, M.W., Chang, Y.C., Lin, Y.N., Ho, Y.H., Weng, W.C., Huang, C.J., Chang, B.E., Yao, C.L., Lee, H. (2017) Activation of Lysophosphatidic Acid Receptor 3 Inhibits Megakaryopoiesis in Human Hematopoietic Stem Cells and Zebrafish. Stem cells and development. 27(3):216-224
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