Genomic Feature
zf3139
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 21: 15825852 - 15825872 (GRCz11) (1) Details
- Nucleotide change
- CAGCGCTCAGCACTGGTCTCA/TA
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 2 bp inserted / 21 bp deleted (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- None
- Flanking Sequence
-
TGAAGGGGGGCTAATAATTCTGACTTTAACAGTACATAAATATCATTTATTTTATAGGCTAGCAATTGTTTACAGTTTAGCCACAGTTACTTCTGACCCATGATTCACAGAGATCATTATGAGGCGTAAGAAAAAGAATGAGTTTTAAGACGTTTAAAATGAAAACAAACCATTTCACAAAATATTTCTAAACCGCCACCAAATATTGTCTTTCACCTCAGAAACTAATATAGGCTAGTAATTGTTCTCACTGGTTTTGCCAACAGTGATTTAATTTGTTCAATTTCGATAGGCTACTGAAAATATTCTGATTGAAGACTGATGTCATTATGTTTAACGCCAATAACGTCTCCTGATATCATTAGACCTGACTGGATGTGTATTTGACCTTCTTCCGAGTATCTGCACTCACTCAGTGTGTGTGGTTCCTCAGTGATGGTGCTGGTCTGCAGGCTGCTGTTGGTCATGGGGCTGATGCTGTGTCTGAGTGCTCAGTTGAG
CAGCGCTCAGCACTGGTCTCA/TA CGGCTGGTATCCTGGAGGAAAGAGAGAGATAGACCTCTACGACACCTCAGAGGTGGGACAATATTCATCAACAACATATACTTTATTTTAAAACTTTACATTAGTAAGGTATTTAATCTACTAGCTATACAGTTGAAGTCAGAATTATTAGCCCCCCTTTGGTTTTTTTCATTTTTAAAAATTCCCAAAATGATGTACGGAAATTTTTACAGTATGTCTGATAATATTTTTTTCTTCAGGAGAAAGTTGTATTTGTTTTATTTTGGCTAGAATAAAAGCAGTTTAAATTTTTTTTAAACATCTTAAGGTCAAAATTATTAAGCTCGTTAGGCTATTTTTTTCAACAGTCTACAGAACAAACTATCGCTATACAATACCTTGTCTAATTACCCTAACCTGCCTAGTTAACCTAACTAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTCTTGGAAAATATCTAGTAAATATTATTTACTGTCATCAT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| gnrh2zf3139/zf3139 | Homozygous | ♀+/- ♂+/- | 3 figures from Marvel et al., 2019 | 3 figures from 2 publications | |
| gnrh2zf3139/zf3139; gnrh3zf713/zf713 | Complex | Fig. 1 from Marvel et al., 2018 | 8 figures from Marvel et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Marvel, M., Levavi-Sivan, B., Wong, T.T., Zmora, N., Zohar, Y. (2021) Gnrh2 maintains reproduction in fasting zebrafish through dynamic neuronal projection changes and regulation of gonadotropin synthesis, oogenesis, and reproductive behaviors. Scientific Reports. 11:6657
- Marvel, M.M., Spicer, O.S., Wong, T.T., Zmora, N., Zohar, Y. (2019) Knockout of Gnrh2 in zebrafish (Danio rerio) reveals its roles in regulating feeding behavior and oocyte quality. General and comparative endocrinology. 280:15-23
- Marvel, M., Spicer, O.S., Wong, T.T., Zmora, N., Zohar, Y. (2018) Knockout of the Gnrh genes in zebrafish: effects on reproduction and potential compensation by reproductive and feeding-related neuropeptides. Biology of reproduction. 99(3):565-577
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