ZFIN Feature: zf3114

Notes

Comment	Citation
This line was created using 2 CRISPRS: - 5'-GGAGAGACAATTTTTTTATG-3' This ...	Torbey et al., 2018

Genome Browser

Genome Build: GRCz11Chromosome: 12

Variants

Variant Type: Small Deletion
Variant Location: Chr 12: 8559687 - 8561114 (GRCz11) (1) Details
Nucleotide change: TAATGCTCTAGAGCAGTGGCTCTCAAACTTTTTTCATCAAGTACCACCTCATAAAAAAATTGTCTCTCCACGTACCACCAAAATGAGCAGTATTGAAATACAATAGCGTAGTAGGCCCAGTAAAGCAGCTACAACTCTGCACAGTTTAAAAAACGTGGCAAATTACCTCAGAAATATAGGCTATATGTCATATATGGCATATTATATACATCATTTTTGATACATTTTAAAATGTGTGTAGCATGTACAAAACATATTTCATTCTTCCACTTACCACTAGAAGGAAGCCTGCGTACCACAGTTTGAGAACCACTGCTCTAGAGTAATTTTCAAGACACGATTCCAATCCACTCCAAACCAGTTTCTGTGTGAAAGCCTCACACCTGACAGCGGTGAGATCTGTCTGCTAGTTTAACATGTGTAAGAATATTTGTCAGGCACATTAGCTCACCGCAGGGTTCCCATTGTGTCCCCCGAGGAGGCCTTAAAAAATCCCCCCTCACATCCCCGTTGGCTCTTTTAGGGCGCTGTGTGTAGGAGGATATGTGGGATTCCCCATACAAGCGCTCCAAAAGCACACAGGAGAACCTGGACAGAAGACCCGCTGTAAGCAGAATGTCTGGAGTCGGGACTCTCCTCTATAGCTTGGCTGGCTCATCATTACTTTTGAGGGCCGAATCGAGGCAGGTGGAAGAGGCGACGGCTCGTCCTCCTACACGCAGATTCCAGTGGACGTCAAGCTCTCGTTTTCTCACAGCTGTCGACTGCTGATGTGCTGACAGAAGAAGAGCTGGAGATGAACACACACACACACACAGGAGAGAAGAATAGCTTAGTACTGACTTGATGCTGTGCGCTCAAATGATTTTAGCTGCTTGTCGAAATTACTTATTTAAAATGAGCTGAAACAACACAATTCTGGAGGTGTTTTTGGTGGAGACCTAATTGTTTTACTCTGCATTTTTATACTGTGTGCTGCACTCTAACATAATCATTAAGTAAGTTAACTATTTTTTTCCAATTTAAATGGATTAAACTTTTTAAAAAAATAAGTTGTCCCCCGCCCCCAACACCCCCCCCCCTCTCTCAAAAAAAAACAAGAAATGTGTTGTTTCCAACATAGGCTCTTTAAAGAGTGTACTATCTCAGTATACCGTCTTCTTGTCAGAGAAAATAAATATAAAAATAAATTGTAGTAATGTGTGAAGGTATTGGTCACCTACACTGTAAAAATGCAGGGTTCCACACAATTCCCAACACAAACTGATTAAGTTAACTTAAAACTTTTAACAAATTTATGTGGATTAAACAGAAAAAAATAAGTTGTCCCAATTAAATCTCAAGAATTCTGTTGTTTCAGCTCATTTTAAAGAAATAGTTTGAATGAGCAAAAAAAAAAGTTTTTTTTGAGTGGAACAGTTTTTGTTG/-
Variant Notes: None

Effect on DNA/cDNA, transcript, protein (from publications)

DNA/cDNA Change: 1428 bp deleted (1)
Transcript Consequence: None
Protein Consequence: None

Sequences

Flanking Sequence: TACATACATATATATATATATATATATATATATATATATATATATGTATATATGTATATATATGTATATATATATATATATATATATATATATATATATATATATATATATATATATGTATATATATATATATATATGTATGTATATGTGTGTGTGTGTGTGTGTGTGGGAAGCAAATTATAGATAAATTTTGTAAAACAATTCTTATATTATCCTTATTTTTTTAATTCAACTATAGGGGTGCAGCCGAGTAAGGAGCCTTAGAAGATAATGTGCCCAGGGGCCACTGAGTTCTAAATCCGGGCCTGCTTCCTGTCCTTCATCTGAGCTTTTAGGTTGTCACGAAAAAAACTCTTTATGTGAATGAAGAAAAAACTTAATTATGTGAATTTAGCTCATTTCATATAATTAGTTTGAACAAGCAGCAAAATCCTTTCTTTTGAGTGTGTACAAGTAAATAATGAGCAAATAATTGCAGAAATGTGTGTGAACTATCCCTT
TAATGCTCTAGAGCAGTGGCTCTCAAACTTTTTTCATCAAGTACCACCTCATAAAAAAATTGTCTCTCCACGTACCACCAAAATGAGCAGTATTGAAATACAATAGCGTAGTAGGCCCAGTAAAGCAGCTACAACTCTGCACAGTTTAAAAAACGTGGCAAATTACCTCAGAAATATAGGCTATATGTCATATATGGCATATTATATACATCATTTTTGATACATTTTAAAATGTGTGTAGCATGTACAAAACATATTTCATTCTTCCACTTACCACTAGAAGGAAGCCTGCGTACCACAGTTTGAGAACCACTGCTCTAGAGTAATTTTCAAGACACGATTCCAATCCACTCCAAACCAGTTTCTGTGTGAAAGCCTCACACCTGACAGCGGTGAGATCTGTCTGCTAGTTTAACATGTGTAAGAATATTTGTCAGGCACATTAGCTCACCGCAGGGTTCCCATTGTGTCCCCCGAGGAGGCCTTAAAAAATCCCCCCTCACATCCCCGTTGGCTCTTTTAGGGCGCTGTGTGTAGGAGGATATGTGGGATTCCCCATACAAGCGCTCCAAAAGCACACAGGAGAACCTGGACAGAAGACCCGCTGTAAGCAGAATGTCTGGAGTCGGGACTCTCCTCTATAGCTTGGCTGGCTCATCATTACTTTTGAGGGCCGAATCGAGGCAGGTGGAAGAGGCGACGGCTCGTCCTCCTACACGCAGATTCCAGTGGACGTCAAGCTCTCGTTTTCTCACAGCTGTCGACTGCTGATGTGCTGACAGAAGAAGAGCTGGAGATGAACACACACACACACACAGGAGAGAAGAATAGCTTAGTACTGACTTGATGCTGTGCGCTCAAATGATTTTAGCTGCTTGTCGAAATTACTTATTTAAAATGAGCTGAAACAACACAATTCTGGAGGTGTTTTTGGTGGAGACCTAATTGTTTTACTCTGCATTTTTATACTGTGTGCTGCACTCTAACATAATCATTAAGTAAGTTAACTATTTTTTTCCAATTTAAATGGATTAAACTTTTTAAAAAAATAAGTTGTCCCCCGCCCCCAACACCCCCCCCCCTCTCTCAAAAAAAAACAAGAAATGTGTTGTTTCCAACATAGGCTCTTTAAAGAGTGTACTATCTCAGTATACCGTCTTCTTGTCAGAGAAAATAAATATAAAAATAAATTGTAGTAATGTGTGAAGGTATTGGTCACCTACACTGTAAAAATGCAGGGTTCCACACAATTCCCAACACAAACTGATTAAGTTAACTTAAAACTTTTAACAAATTTATGTGGATTAAACAGAAAAAAATAAGTTGTCCCAATTAAATCTCAAGAATTCTGTTGTTTCAGCTCATTTTAAAGAAATAGTTTGAATGAGCAAAAAAAAAAGTTTTTTTTGAGTGGAACAGTTTTTGTTG/- GGTACATTTAAAAAAATATATATTCTTACGGCCACAACTGCATTGTGGATACATCGGTGCCGCTTTAGAGGCGTTGCTCG ...
Additional Sequence: None

Fish

Show only fish without sequence targeting reagents

Fish	Genomic Feature Zygosity	Parental Zygosity	Affected Genomic Regions	Gene Expression
en.egr2b_enha^{zf3114/zf3114}	Homozygous	Unknown		4 figures from Torbey et al., 2018
en.egr2b_enha^{zf3114/zf3114}; en.egr2b_enhb^{zf3116/zf3116}	Complex			Fig. 4 from Torbey et al., 2018
en.egr2b_enha^{zf3114/zf3114} + CRISPR3-en.egr2b_enhc + CRISPR4-en.egr2b_enhc + CRISPR5-en.egr2b_enhc + CRISPR6-en.egr2b_enhc	Complex		en.egr2b_enhc	Fig. 6 from Torbey et al., 2018
en.egr2b_enha^{zf3114/zf3114} + CRISPR1-en.egr2b_enhd + CRISPR2-en.egr2b_enhd + CRISPR3-en.egr2b_enhd + CRISPR4-en.egr2b_enhd	Complex		en.egr2b_enhd	Fig. 5 from Torbey et al., 2018
en.egr2b_enha^{zf3114/zf3114} + CRISPR3-en.egr2b_enhe + CRISPR4-en.egr2b_enhe + CRISPR5-en.egr2b_enhe	Complex		en.egr2b_enhe	Fig. 5 from Torbey et al., 2018
en.egr2b_enha^zf3114/+ + CRISPR1-en.egr2b_enhd + CRISPR2-en.egr2b_enhd + CRISPR3-en.egr2b_enhd + CRISPR3-en.egr2b_enhe + CRISPR4-en.egr2b_enhd + CRISPR4-en.egr2b_enhe + CRISPR5-en.egr2b_enhe	Complex		en.egr2b_enhd en.egr2b_enhe	Fig. 6 from Torbey et al., 2018
en.egr2b_enha^{zf3114/zf3114} + CRISPR1-en.egr2b_enhd + CRISPR2-en.egr2b_enhd + CRISPR3-en.egr2b_enhd + CRISPR3-en.egr2b_enhe + CRISPR4-en.egr2b_enhd + CRISPR4-en.egr2b_enhe + CRISPR5-en.egr2b_enhe	Complex		en.egr2b_enhd en.egr2b_enhe	2 figures from Torbey et al., 2018
en.egr2b_enha^zf3114/+; en.egr2b_enhc^zf3117/+ + CRISPR1-en.egr2b_enhd + CRISPR2-en.egr2b_enhd + CRISPR3-en.egr2b_enhd + CRISPR3-en.egr2b_enhe + CRISPR4-en.egr2b_enhd + CRISPR4-en.egr2b_enhe + CRISPR5-en.egr2b_enhe	Complex		en.egr2b_enhd en.egr2b_enhe	Fig. 6 from Torbey et al., 2018

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Supplemental Information

Genotyping protocol: None

Citations

Include unpublished citations

Torbey, P., Thierion, E., Collombet, S., de Cian, A., Desmarquet-Trin-Dinh, C., Dura, M., Concordet, J.P., Charnay, P., Gilardi-Hebenstreit, P. (2018) Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation. PLoS Genetics. 14:e1007581

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