Genomic Feature
mi371
- ID
- ZDB-ALT-191114-4
- Name
- mi371
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Kuwada Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 2: 43578466 (GRCz11) (1) Details
- Nucleotide change
- A/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 1 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TACACCAGGAATTATTGGTTGTGTACACCTGAAGTAGTTCCAGCCAGATCTTGGTGGCTTTAGTTAATAACTCACTTGTGTTCAGTACAAACTCCAGGGCACGTTGGGCAGATTTCACAAGTCGGACCCTGAAACTTGGTGTCGGTACATTTACAGGCGCCGCATTCACAGTTGCCGCGGCCGTTACAGATCTGTTTATTGCTGGCCAGACAGGTGGAGGTGTCCAGAGAGCAGTCGCACGCGCTGCCGGTGTAGTTAGCATCACAGATACACTTTCTGCAATCACACCGACCGTGACCTGAGAGACGGAGAAACACTTTTAGGTTGAAGCTTTAATCTGTTAAAACATTTACAGTAATCATTCATGTGTCAAGATTCAATCAGAGCAGTGTTATTGTCAGTATATTAGCATTTTAAACACATTTTGTGGTATTTATATACATATATAAAAAAATCTCATTTGTACCTCCACAGAGCTTGTTGTTTGAGCGATCGCAGTT
A/- AAGTTGTCGCACTCGCAGAACTTTCCACTGTATCTCTCCTCAGGGTTGTCTCTTTTCTTGCATTCGCACGTTCCACAAACGCAGTCTCCGTTGTTGCTGCAGATGTCAGTGCCATTATCCATACGACAGTTTGCGTCCAAATCTTCAGTCCTCACCTCATCTTTGCTACATTCACAAACTCTGCCAATGCGTCCCTCATTGCACCTGAATAAGACCATATTTATCAGTTGAGTGTGAGGAGTATACAGATGCTACAGCCAGTTTGAGTGAATAACTCACCTGCACGCTCCACACTCCAGGGTACCATTGCCAAAATGACACACTGGGCTGTTTTTAATCCCATCTTTGTGACACTCGCATTCACAGATGAAGTTGAGGACGACCTCCACCTCCTCAGTGAAGCCCAGCAGTTTAATCTTCATGGTCTCAGACTTTCCATTCAAAGGACAGCCTTTTGCAGTGATCGCCACCTCGAATGCCACCTGTCATGCAGAAAGACA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| itgb1bmi371/mi371 | Homozygous | ♀+/- ♂+/- | Fig. 6  from Rho et al., 2019 | ||
| itgb1bmi371/mi371; y1Tg | Complex | 4 figures from 2 publications | Fig. 5 from Rho et al., 2019 | ||
| itgb1bmi371/+; y1Tg | Complex | 3 figures from Iida et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Chen, Y.C., Martins, T.A., Marchica, V., Panula, P. (2024) Angiopoietin 1 and integrin beta 1b are vital for zebrafish brain development. Frontiers in Cellular Neuroscience. 17:12897941289794
- Rho, S.S., Kobayashi, I., Oguri-Nakamura, E., Ando, K., Fujiwara, M., Kamimura, N., Hirata, H., Iida, A., Iwai, Y., Mochizuki, N., Fukuhara, S. (2019) Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Developmental Cell. 49(5):681-696.e6
- Iida, A., Wang, Z., Hirata, H., Sehara-Fujisawa, A. (2018) Integrin β1 activity is required for cardiovascular formation in zebrafish. Genes to cells : devoted to molecular & cellular mechanisms. 23(11):938-951
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