Genomic Feature
ip7
- ID
- ZDB-ALT-190620-8
- Name
- ip7
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with
- Lab of Origin
- Herbomel Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 3: 22345577 - 22345600 (GRCz11) (1) Details
- Nucleotide change
- TCAGAATGGACCTTCACCGTGTGG/ATT
- Variant Notes
-
tcaga(ATG)GACCTTCACCGTGTGG repalced with ATT
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
AGCATGCATCGGCATGCCACGACGTTAGTCATGCACAGTGTTTTCTGCTCAATATAAGACTACTCATCTGCCATCATTTATTCATATTCAGTGGAATGTATTTATTTTATTGGGATTTGTTTGCACCCTGGGCTCTTAGATACCACACAGATTAATTAAAACCCGAAAGTTGTTACTCTAGCAAAACATATTCCGTTAGCTTCCGTTAGAGATTCTCTTGAATGAACGAACTCGAAAACTCCGCGCAAGACCTTCATGAGCTCGTGAAAAATCCCCTCTTTCTCTTCAAGATGAAAGAATTAATGCGAAATCACGCCTTTTCGATTTGTTCACAAAATACTGTATATAAACTTCAGATACATTGAATCCATCACATAACGACAATCGAGTTTTGGAGGATACTCAACATTTCAAAGAGGTGAGTCAGATTATTGACCCATAATTAACCTGGTAATGTATAGTTTGCATCATACTAATTTCTGATTCCGTATAGGCATCTG
TCAGAATGGACCTTCACCGTGTGG/ATT CCTGGCTGTGCACCTTTTTCTGCTTTGTGCAGGTTTGGTCATTGCCAACAAACTGCAATCTTCAGAAAAACTTAATGAAGAGGACCTATACACTTCTGGAGACTGCGGTAAGATTTATTGCAGATAATCGTCAGTTTTATTATTGTATGTAACGAATAATTAATTGCATATTCAACATGTGTTAGGTCGTCTAACGAATATAATCTTGTTTTAGGGAGGGCTTTTCCCTATGCAATGCCTGGACGACCGCGTTTCTATACCATTCCCGCAAAATGTGTTCGAGTATAACGAGGATCAGGTAAAATCTTTAACACAGCTGTTAATCTATGGGTGCTTGGCATATTTGACACTTCCCAAAAATCTTTCATTTAAATTAATATTTTCTATAGGATGTTTTACAAAATTATATTTGTGCATTAGTTTAGTCAGTACTGAAGCTAAATCTGGAGCTAATCTAATAAAATAACTTTTATAATAATGTAAAAAACAAATAGCCCAAA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| ifnphi3ip7/ip7 (AB) | Homozygous | ♀+/- ♂+/- | Fig. 7 from Maarifi et al., 2019 | ||
| ifnphi3ip7/ip7 + MO1-trim8b (AB) | Complex | Fig. 7 from Maarifi et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Laghi, V., Rezelj, V., Boucontet, L., Frétaud, M., Da Costa, B., Boudinot, P., Salinas, I., Lutfalla, G., Vignuzzi, M., Levraud, J.P. (2022) Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder. Frontiers in cellular and infection microbiology. 12:790851
- Maarifi, G., Smith, N., Maillet, S., Moncorgé, O., Chamontin, C., Edouard, J., Sohm, F., Blanchet, F.P., Herbeuval, J.P., Lutfalla, G., Levraud, J.P., Arhel, N.J., Nisole, S. (2019) TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells. Science advances. 5:eaax3511
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