Genomic Feature
bns292
- ID
- ZDB-ALT-190403-10
- Name
- bns292
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Stainier Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 11: 34780268 - 34780275 (GRCz11) (1) Details
- Nucleotide change
- TTGAACTG/-
- Variant Notes
-
p. Gln67Gly*9
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 8 bp deleted in Exon 3 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
CAGAAGATACAAACCAGGATGATTCAAATGAAGTCTAATGTTTCACAGAGCCAAGCGCAGACTCACCTGCCACTCATTTAGATCCCGAACCTCATTTTTAGGTCTCTCAAGTGCACGTTAATGTCACATTTTAATCACAAAACCTGACGTTTAAGAGCTTCCTGCATCTGTTTGCTTCACAGATTCTGGGGCATTGTTACATATGATCTCTTCATAGTCAAAAGTGGAGCTGTCTTTGCTGTGAGGGGGTGAAGTGAGGATAACATTAGCTAGTCGCTGGGTTTTCTGTGGCTGCTGCTGCTGTGGAATCAGTAGAGGATGCTGGGAGAGAGTCAGTGGGTGCAGTATTTGCTTCACCAGAGGGGGCACTGTCGTTGTCGTCTTCCTGAGGGTAAAGCTCAGGGTATTTCTGCATACACTCCTGCATACCCCGGAAGTTTTCCACACAATCGGAGCCCTTTATCTCCTCTTTGCTATAGTGGAAACATGAAAACGCATCC
TTGAACTG/- CTGTCCACAAGGGCCACTGGCCATGCCGCCCAAACACGGGCAGTTCCAGTTTATGTCGCCATTAGGTAGAATAAGACCTGTGGGATCATAGCAAACGGGTATTGTGGAGATCAATTATAGAAGAGATTTAAATGATGCTAGCTGATATGGCTGCACGATACTGGGAAAAGATCCCATGTTGTTGAGTATTACGAATTTTTGATAACTGTATATAAAGATAGAAAAACCCCATGTTTGATTGTATAGATAATCAACCTATTACACAAAAAAATTGGTATATAAATAAATGTAATTTATCTAGTGCTGCGCAGAGTTGTAGTGATTAACTGCATCCAAAAAAAAAAGTTTGTTTTGGCATAATGTGTGTTTAAATTACTTTCAAGGCCAAAATGACTCCTACCCCAGGGGTAAGAATTTTCTTGGGCTTGGCATGCACGCATACATGCGCGCGCACGCATGCACACATGCACACACACACACACACACACACACACACACAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| chchd4abns292/bns292 (AB) | Homozygous | ♀+/- ♂+/- | 4 figures  from Sokol et al., 2018 | Fig. 6 from Sokol et al., 2018 | |
| chchd4abns292/+ (AB) | Heterozygous | Unknown | Fig. 6 from Sokol et al., 2018 | ||
| chchd4abns292/bns292; cms1Tg | Complex | 2 figures from Sokol et al., 2018 | Fig. 3 from Sokol et al., 2018 | ||
| chchd4abns292/+; cms1Tg | Complex | Fig. 3 from Sokol et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Uszczynska-Ratajczak, B., Sugunan, S., Kwiatkowska, M., Migdal, M., Carbonell-Sala, S., Sokol, A., Winata, C.L., Chacinska, A. (2022) Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish. Life science alliance. 6(1):
- Collins, M.M., Ahlberg, G., Hansen, C.V., Guenther, S., Marín-Juez, R., Sokol, A.M., El-Sammak, H., Piesker, J., Hellsten, Y., Olesen, M.S., Stainier, D.Y.R., Lundegaard, P.R. (2019) Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model. Proceedings of the National Academy of Sciences of the United States of America. 116(48):24115-24121
- Sokol, A.M., Uszczynska-Ratajczak, B., Collins, M.M., Bazala, M., Topf, U., Lundegaard, P.R., Sugunan, S., Guenther, S., Kuenne, C., Graumann, J., Chan, S.S.L., Stainier, D.Y.R., Chacinska, A. (2018) Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish. PLoS Genetics. 14:e1007743
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