Genomic Feature
fu55
- ID
- ZDB-ALT-190319-5
- Name
- fu55
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with
- Lab of Origin
- Lecaudey Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 22: 38049498 - 38049512 (GRCz11) (1) Details
- Nucleotide change
- AACTCGGTCATGAAC/TAACTCGG
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 8 bp inserted / 15 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TCGTCAACTTCCAATGCCGAACATCCATCGTTGCGTTTTGTTTATGAACGAAAGCGTACATAACTGGCTCATTGAATATTCATGAGGGGCTGGAGACGTGATTGAATATTCATAAACTGACAGACAGACACAGGAGCCGCTCAGACTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGCTTGAGTTTACAAACTTTCAGAAACTCCGCGATCGGACGCAGGAGGAACAAAAAACTCTCCAAACTCCACGCGGGACAACATGACAAACGCCTTTCTAGCTTTATGACAACTTTTCGACGACTTACAAACACTTTTCAACTCGGCTGAAACTACTTAAGGACGAAAAACAGGAAAAGTTCCTACAGGAATTTTTTTTTCCATCGGCCATTTTAATCGAAGTTTGTTTTGACCATGAGCGGTAATCCTCTCCAGCCGATACCGGGCCACCAGGTGATCCATGTCGCCAAAGACCTGGACACGGATCTGGAGGCTCTTTTT
AACTCGGTCATGAAC/TAACTCGG CCGAAACCGAGCTCCTGGAGGAACAAGGATATGCCGCAGTCTTTCTTCCAGGAGCCGGACTCGGGCTCCCACTCCCGGCAGTCCAGCGCGGACTCCGGTTCTCTCCCGCCGAGGGTCCACTTTCGCTCGCGCTCATCTCCGGCGTCCCTACAGCTGCCGGCGGGCTCCGTGAGCGGCCCGAGCCCCGGGAGACTCCACTCCCACACCCGGCACCAGTCCTGCGATGTGGCCGAGGAGCTGCCGCTGCCCCCTGGGTGGGAGATGGCCTTCACCCCCAACGGCCAGAAGTACTTTCTCAAGTAAGAGTTCGTTATTACTGGACATTCCTGCACACTGTTTAGTTCACATTACCAGTTAGTGGAGTGCATACAGTGGGGGGAATGAGTATTGAACACGGTCCTGTTTTGATTTCCTGGGAATAATATTCATAAAGGAGCTGTTGATATGGAGTTTAACCAGATTTTGGTAGAAACCAAAACAATACAAACATAAAAACGAAA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| wwtr1fu55/fu55 | Homozygous | ♀+/- ♂+/- | 3 figures  from Dingare et al., 2018 | 3 figures from Dingare et al., 2018 | |
| wwtr1fu55/+ | Heterozygous | ♀+/- ♂+/- | Fig. 2 from Dingare et al., 2018 | 2 figures from Dingare et al., 2018 | |
| wwtr1mw49/+; wwtr1fu55/+ | Complex | ||||
| yap1fu48/fu48; wwtr1fu55/+; mw50Tg | Complex | Fig. 5 from Voltes et al., 2019 | |||
| yap1fu48/+; wwtr1fu55/fu55; mw50Tg | Complex | Fig. 5 from Voltes et al., 2019 | |||
| wwtr1fu55/+; mw50Tg + MO1-yap1 + MO4-tp53 | Complex | Fig. 5 from Voltes et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Voltes, A., Hevia, C.F., Engel, C., Dingare, C., Calzolari, S., Terriente, J., Norden, C., Lecaudey, V., Pujades, C. (2019) Yap/Taz-TEAD activity links mechanical cues to progenitor cell behavior during zebrafish hindbrain segmentation. Development (Cambridge, England). 146(14):
- Dingare, C., Niedzwetzki, A., Klemmt, P.A., Godbersen, S., Fuentes, R., Mullins, M.C., Lecaudey, V. (2018) The Hippo pathway effector Taz is required for cell morphogenesis and fertilization in zebrafish. Development (Cambridge, England). 145(22):
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