Genomic Feature
swu47
- ID
- ZDB-ALT-181217-3
- Name
- swu47
- Synonyms
-
- Delta 1 taz (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Huang&Ruan Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 22: 38049698 (GRCz11) (1) Details
- Nucleotide change
- C/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 1 bp deleted in Exon 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
AGAAACTCCGCGATCGGACGCAGGAGGAACAAAAAACTCTCCAAACTCCACGCGGGACAACATGACAAACGCCTTTCTAGCTTTATGACAACTTTTCGACGACTTACAAACACTTTTCAACTCGGCTGAAACTACTTAAGGACGAAAAACAGGAAAAGTTCCTACAGGAATTTTTTTTTCCATCGGCCATTTTAATCGAAGTTTGTTTTGACCATGAGCGGTAATCCTCTCCAGCCGATACCGGGCCACCAGGTGATCCATGTCGCCAAAGACCTGGACACGGATCTGGAGGCTCTTTTTAACTCGGTCATGAACCCGAAACCGAGCTCCTGGAGGAACAAGGATATGCCGCAGTCTTTCTTCCAGGAGCCGGACTCGGGCTCCCACTCCCGGCAGTCCAGCGCGGACTCCGGTTCTCTCCCGCCGAGGGTCCACTTTCGCTCGCGCTCATCTCCGGCGTCCCTACAGCTGCCGGCGGGCTCCGTGAGCGGCCCGAGCCC
C/- GGGAGACTCCACTCCCACACCCGGCACCAGTCCTGCGATGTGGCCGAGGAGCTGCCGCTGCCCCCTGGGTGGGAGATGGCCTTCACCCCCAACGGCCAGAAGTACTTTCTCAAGTAAGAGTTCGTTATTACTGGACATTCCTGCACACTGTTTAGTTCACATTACCAGTTAGTGGAGTGCATACAGTGGGGGGAATGAGTATTGAACACGGTCCTGTTTTGATTTCCTGGGAATAATATTCATAAAGGAGCTGTTGATATGGAGTTTAACCAGATTTTGGTAGAAACCAAAACAATACAAACATAAAAACGAAATAAAACAAAACAAAAGTGAGTTCTGTGTAATAACAATGAAATAATACAAGTACTGAACTACTGGAATGTATTTAATACTGTAAATAAAAGTCTTTTTTAAAGGCTCCTCTGATATGGAGATAGAAGGCACATGCATTACTCAAGTGTGAGTTTCTCACAGACAGTGTCAAAATCTTGATGCTTCTG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| wwtr1swu47/+ (AB/TU) | Heterozygous | ♀-/- ♂+/+ | Fig. 2  from Yi et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Yi, X., Yu, J., Ma, C., Dong, G., Shi, W., Li, H., Li, L., Luo, L., Sampath, K., Ruan, H., Huang, H. (2019) The effector of Hippo signaling, Taz, is required for formation of the micropyle and fertilization in zebrafish. PLoS Genetics. 15:e1007408
- Yi, X., Yu, J., Ma, C., Li, L., Luo, L., Li, H., Ruan, H., Huang, H. (2018) Yap1/Taz are essential for the liver development in zebrafish. Biochemical and Biophysical Research Communications. 503(1):131-137
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