Genomic Feature
zf1089
- ID
- ZDB-ALT-180905-2
- Name
- zf1089
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one insertion (1)
- Protocol
- embryos treated with zinc finger nuclease
- Lab of Origin
- Zhdanova Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Insertion
- Variant Location
- Chr 16: 252391 - 252392 (GRCz11) (1) Details
- Nucleotide change
- -/GCAG
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 4 bp inserted in Exon 12 (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- None
- Flanking Sequence
-
TCCAGCATTACTAGCTCTTGTTTTAAAGTTAAAACTCTTCACTTTTGAGATGTGTGATGGTCAACACAGCTAGATCTAAATGACAATATAGAGGGAAAGTTGAATATCAAATTACAGCCTAAAGTTATGAAATAAAATGAAAAATACATACATTTAATGACAACAGTCAACATAATAATGCGGATTTTGATAATGTCCTTTGTTTGTTTATTTGTGCTACTTTAACGATCATCACACCTTCAGTAATGTTGCATGCTCTTGTTTTTGAGGTTGTAATATTGTTTCAGCTCAATGTGGATCAATATCTCTCACTGTGGAGTGTTGTGGTGCTGAACAGAGAGAGAACACTGTAATGATGGAGACGAGTGGTTGGTCACACTGTCTGAAAACACATCAGTCTCTAACGCAGCATCAGCTTGCAGGAGAAAATGCTGCAGCTCACCGTAAAACCAGGCGATGCCGATGGCCTCAATTAGTACTCCAAAGAGAATTGACGTCCCC
-/GCAG GCAGCGAAGTGGTCCAACAGCGTAAACACATAGATTCCACCCTACAAAGAGAGCAGCAGAGTAAACACGTAGATACCACCCTACAGAGAGAGCAACAGAGAGATGAAGACACAGTGATTAACCCTACGATGAACATTTCCCCAAGTGCATTTAATGGAGATATGTTTAAACAAAATGCTCTAGTAACACATCTATTTACTTTCTCTTCGCCATGATGACAGTACATTATATTTTACTAGGTATTTTGCAAGGTGCCATTATTCAGCTTAAAGTGACATTTAAAGGCTTCACTAGGATAATTCGGCAAGTCACTGCAGTGCCTTGTTTTGTAGACATTCATAAATTCATTCATTTTCCTTTGGCTTAGTCTCTATTTCTGACGTTGCCACAGTGGAATGAACCACTAATTATTCTAGCATATGTTTTACACAGCAGATGTCCTTACAGCTGCAATCCAGTACTGGGAAAGACCCATACACACTCATGCACAACGGCCAGTTT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| slc6a3zf1089/zf1089 | Homozygous | Unknown | 6 figures from 2 publications | ||
| slc6a3zf1089/zf1089; nkGCaMPHS4aTg; s1013tEt | Complex |
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Supplemental Information
- Genotyping protocol
- None
- Kacprzak, V., Patel, N.A., Riley, E., Yu, L., Yeh, J.J., Zhdanova, I.V. (2017) Dopaminergic control of anxiety in young and aged zebrafish. Pharmacology, biochemistry, and behavior. 157:1-8
- Riley, E., Maymi, V., Pawlyszyn, S., Lili, Y., Zhdanova, I.V. (2017) Prenatal cocaine exposure disrupts the dopaminergic system and its postnatal responses to cocaine. Genes, brain, and behavior. 17(4):e12436
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