Genomic Feature
sd49
- ID
- ZDB-ALT-170119-5
- Name
- sd49
- Synonyms
-
- sd43 (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Traver Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 2: 3201477 - 3201504 (GRCz11) (1) Details
- Nucleotide change
- CACGGCTTACTTCGGGTAGGCAGGACAA/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 28 bp deleted at Exon 1 - Intron 1 Splice Junction (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TAACGTGTACTTAATTAATATGAAATTAGAGAAGGCTACTTATTTTTGTGGGGATACATGTCAGAATGTTTACGATTAGCCTATATGCTAATTGCTCATGTTTACACCAAATCTATTAGCCGTCCCAATTTGGCAAACGTAAATAATTAAGCCAGACTTACTTTTAAATCCAGCTGCTCGGTCAGCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCCTGCTGTAAGTGAATGGGGAGGAGCGCAGTGCGAAATCCTCGCAGTGTATAAGAAGTGCGGTTCTCACAAGCAGGGATTTTACACAGCAACTCAGGACGAACGAAATGAGCTGCCCCAGAGCCGCTACAAAATGCTGGATGGACACCTTCTCCTGGGATGGTTATCATTTACCATTATAGTGCATCTGATCAGCCTGCCCGGACCGAG
CACGGCTTACTTCGGGTAGGCAGGACAA/- TTCTTTCTTAAGCTCTTTCCTAATGCTTTTTCTCATGTATGAATAGACAAAAACAGAGATGTGATATAATGCATCAACATCATGAACGAAAGAGCTCCTTACTGGTGTTGAGAAATACTGTTTAGTAATTGTTTGTTCACAAACAACCTGTTGCGTTTCAGAGTGATGTTCTCATTAATGTTTGCATGATGTTGCTTGCAGATTTATTAAACAGCACTAAACTATATCACATCAGATCGTCGTTTATCATTCAGTGCTGCGCTTTGAATGGCAGGTACAAGCCGGTCAGGTTGGTCCTTTTAATAGATGCTTGTAGAGGAATGAAAAACATCAGACACGAGCAAGCTCTCAACAGCTGTTAACAATAAAGCTACGAGGATCTCTAACCTGGTGGCCAAAACGTCTGTTCAGATCGCAGATAATATTTCTTCATCCAGCATAAACACTCGTTTTTTTTTTTCTTTTTTTGGCACCCCCGCTTTGCTCGCTCGCTAAGCTTA - Additional Sequence
- None
Fish
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Supplemental Information
- Genotyping protocol
- None
- Paolini, A., Sharipova, D., Lange, T., Abdelilah-Seyfried, S. (2023) Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling. Development (Cambridge, England). 150(18):
- Paolini, A., Fontana, F., Pham, V.C., Rödel, C.J., Abdelilah-Seyfried, S. (2021) Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish. Cell Reports. 37:109782
- Grainger, S., Nguyen, N., Richter, J., Setayesh, J., Lonquich, B., Oon, C.H., Wozniak, J.M., Barahona, R., Kamei, C.N., Houston, J., Carrillo-Terrazas, M., Drummond, I.A., Gonzalez, D., Willert, K., Traver, D. (2019) EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nature cell biology. 21(6):721-730
- Grainger, S., Richter, J., Palazón, R.E., Pouget, C., Lonquich, B., Wirth, S., Grassme, K.S., Herzog, W., Swift, M.R., Weinstein, B.M., Traver, D., Willert, K. (2016) Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells. Cell Reports. 17:1595-1606
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