Genomic Feature
sm6a
- ID
- ZDB-ALT-161103-10
- Name
- sm6a
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Yiyue ZHANG Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 24: 40826412 - 40826419 (GRCz11) (1) Details
- Nucleotide change
- ACTCTTAG/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 8 bp deleted in Exon 2 (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
ATAATATAATATAAAATAATAAAATATAATATAATATAATATAATATAACATAACATAACATAACATAACATAACATAACATAATATAATATAAGATAACATAATATAATATAATTTAACATAATATAATGTAATGTAATGTAATATAATATATAGAACTGTAATTTCTAACCCCGACCGTTTAACAGATCACATGTCTTGACTCAATATACAAAAAAAAAAAAAAAAAAAAAAAAACAGACGCAAATAAAGATAGAAATGTGTTGGTGTGTTTGTGCGTTATTCTGTTATATGTTTGTGTGTCAGTGTGTTTGTTTGTTTGTTTGTTAGTCTCTGTGTGTTTGTGTGCAAGAATTTTTGTGTTAGTGTGTATGTCTGTGTGTATGTTAGTGTGTTATTACCTGTGTATGTGCAGAACTCTGCTGCACTGAGCGCTCAGTGTTGGTGTTTGGGTTGTTCAGACAGGAGGAGTACGGTAAATAACCCATCATCACCTCGGG
ACTCTTAG/- TAAAGCTGATGGTCTGAGTATACAGGGCCGAGTCCATCGGAGTCTGAGCGCTGGAGTCTGAAGACGCCTCGTGCACAGAGAAGATGTTGTCAGACACCGACATCTGTGGAGGAAAATGACCTATACAGTAAAAAAATGACCCATACTGTGTTCAGAATTTCAATGCTATCACTGATTATCACTAATTATTTACTTCTATAAATGTGTGTATATATGAGTATTAATATTGATCCAGTAAAGGAATAACTAGCTTGATTAGGCAAGTTAGGGGAATTGTGCAAGTAATTGTATAACAGTGGTTACAGTGAACTTACATTTCAAACTCCATATTTCTGATCAACTAAACACAAGATTGTAAATTTAACAAAGTTTACTAAACTTTAAATGTTAAGTTGATTAAACATGCACACAAGTTAATACAACTAATCGACTGTGTTAAACAAAATGTATAAAATCAGGAGTTGAAAGCTTAACTGCAACTGCTATCCTCTAACTGTGGA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cebp1sm6a/sm6a | Homozygous | ♀+/- ♂+/- | 2 figures from Jin et al., 2016 | 3 figures from Jin et al., 2016 | |
| cebp1sm6a/+ | Heterozygous | Unknown | Fig. 5 from Jin et al., 2016 | ||
| cebp1sm6a/sm6a; i114Tg | Complex | 2 figures from Jin et al., 2016 | 2 figures from Jin et al., 2016 | ||
| mybhkz3/hkz3; cebp1sm6a/sm6a | Complex | Fig. 4 from Jin et al., 2016 | Fig. 4 from Jin et al., 2016 | ||
| mybhkz3/hkz3; cebp1sm6a/sm6a; i114Tg | Complex | Fig. 4 from Jin et al., 2016 | Fig. 4 from Jin et al., 2016 | ||
| mybhkz3/+; cebp1sm6a/sm6a | Complex | Fig. 5 from Jin et al., 2016 | |||
| mybhkz3/+; cebp1sm6a/+ | Complex | Fig. 5 from Jin et al., 2016 |
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Supplemental Information
- Genotyping protocol
- None
- Li, G., Sun, Y., Kwok, I., Yang, L., Wen, W., Huang, P., Wu, M., Li, J., Huang, Z., Liu, Z., He, S., Peng, W., Bei, J.X., Ginhoux, F., Ng, L.G., Zhang, Y. (2024) Cebp1 and Cebpβ transcriptional axis controls eosinophilopoiesis in zebrafish. Nature communications. 15:811811
- Jin, H., Huang, Z., Chi, Y., Wu, M., Zhou, R., Zhao, L., Xu, J., Zhen, F., Lan, Y., Li, L., Zhang, W., Wen, Z., Zhang, Y. (2016) cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood. 128(3):415-26
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