Genomic Feature
a142
- ID
- ZDB-ALT-140611-7
- Name
- a142
- Synonyms
-
- allele 3, allele 28 (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- TALEN
- Lab of Origin
- Schier Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 1: 19673494 - 19673510 (GRCz11) (1) Details
- Nucleotide change
- TGTTTTGTACCATGTTT/TGTTTTGTTT
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 10 bp inserted / 17 bp deleted (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- None
- Flanking Sequence
-
TGTTCACAAGAGTCGTTTGCTCGTGAATCGGTCTCACATCTTTGTTTCACGTGCAGTCCGCAACACACAATTCGCAAATTTGAAATTCAGACTATAGCTATACAGTTCATTATGGCATCAAAGACTCCATGAATAACGTTTACCATTCTTTGCATATAATTTTTCAAATACAAATGAAAGTTACATTGGGTTAGAAAGCAAAAAGGTTCTTCCTCAAGGAGAATCAAGTGTGATTTAGACTACAAAATAGTCTAGATATATGGTTGACTGAAATATTTTCTTTTTAATCGACGTGACTTAATATTTTACATAGGTTTTTTTCAATCTATAAATTACAGGTAGGCTAGCCTACAACCGCCAACAGAACATTTTAAGTTTGTCTAAATGTTCGGAGCTTTGATTCAGTTCTTCGCCTCACAACATACTCGAATCGTTTGCCTCATGTTGTTTAGCCTAAAACTTGTCTATTTTAAGATGTGGTGGTGTTGAGTAGCTTACCG
TGTTTTGTACCATGTTT/TGTTTTGTTT ATCTGCGCTGATGAGGACCAGCACTGTCAGCAGCAGCAGCAGCAGATACAGCGGGTGGAAGAATCTCATGGTGATGCTCAGGGTGGTTTGGTCCGCGGCGCAGACTCGACTCTCCTCACAGGATGTCCGCGGTTCCTCAGACGATAAATTCTGTCGGATGTGCAGGTAACGGACTGTAGAAATCCTCTTATGTGTCTGTCGCTCTCAGCAAGTGTTCTCAGATCTCATATAAGTTGAGTTATATAGAAGACACGCAGTTGTAGCCAGCTCTCGGTCTCTCCAACTTTTTCAAAGTTTGAGAGGGCGATATTCACTCTCTCTTCTCTCTCTGTCCTCTGAGGGATGGATAGATAGACAGATGACCTGATGAGTGGGAATGTTCAGTTGAGACAATGTAGTTTCACCCCCTCTTTATACAGACAAGAGAAAGGGGAGGAGAGGGCACGACAGAGGAGGGGTATGAAAGACCTAAAACTGGGTGGGGACAGGGCATCACACAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| apelaa142/a142 | Homozygous | ♀+/- ♂+/- | 5 figures  from Norris et al., 2017 | 5 figures from Norris et al., 2017 | |
| apelaa142/a142 (AB/TL) | Homozygous | ♀+/- ♂+/- | |||
| apelaa142/+ (AB/TL) | Heterozygous | Unknown | |||
| apelaa142/a142; cz3331Tg | Complex | Fig. 5 from Norris et al., 2017 | Fig. 5 from Norris et al., 2017 | ||
| cxcr4aa169/a169; apelaa142/a142 | Complex | Fig. 7 from Norris et al., 2017 | Fig. 7 from Norris et al., 2017 | ||
| lft2a146/a146; apelaa142/a142 | Complex | 2 figures from Norris et al., 2017 | 2 figures from Norris et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Norris, M.L., Pauli, A., Gagnon, J.A., Lord, N.D., Rogers, K.W., Mosimann, C., Zon, L.I., Schier, A.F. (2017) Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLIFE. 6
- Pauli, A., Norris, M.L., Valen, E., Chew, G.L., Gagnon, J.A., Zimmerman, S., Mitchell, A., Ma, J., Dubrulle, J., Reyon, D., Tsai, S.Q., Joung, J.K., Saghatelian, A., and Schier, A.F. (2014) Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (New York, N.Y.). 343(6172):1248636
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