Genomic Feature
mq6
Notes
No data available
Variants
- Variant Type
- MNV
- Variant Location
- Chr 15: 27391864 - 27391868 (GRCz11) (1) Details
- Nucleotide change
- CAGGC/TAGCA
- Variant Notes
-
homozygous viable
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- None
- Transcript Consequence
- None
- Protein Consequence
- Amino Acid Substitution (1)
- Flanking Sequence
-
TGAAAGTTGTACTTCCATGTAAAATAAAATTGAGATGATGCATGGATATCCTGAGAAAAATGGAAATCCCAATCTTTATGAATTGAAATTTTTAACCCCTCATTGAACTAATATTTGGATAAACTTACAGAAATGCTTCAGGAGAAGGCCTCAGTTGTGGCTGATGAAGGAATGACCGTTGCCCAGTCGGGTGGGCGTCCTGAGCTGGCCAGCGATTCCTCACATCTGGGCCTGCCTACAACTCCCAGCAATCCCCAGAACAATGAACCTGACCAGGTAGGCAATCAGTGGCATGCTTTCAATGGCTCTTGCCATGTAGGGTATCTGTGAATAGATGTTAAACAACATTAAGTTTGATTCCACCGACAATGACTCATTATGATTTTTCTTTTTTGTCTGTGTGCACCTTCAGAGCATTGAAAACATCAAAGTGGTTCTTCATGACAGGGAATTATGGAAGAAGTTTCACGAGGCTGGAACCGAGATGATCATCACCAAAG
CAGGC/TAGCA AGGCAAGAAGAGCGCCATTTTCATCCACCCATTCGCTTAGAGACACACACAGAGAAAATGGTAGTGCAAACATAACTAGGCCATCTCGCTTCCAGTAAGAAACGCAAATGTAAAACTTTGTTTTACCAAAAGCCTCAGTCGCATGAAATACTAAGTCGCTTCTTGTGGAATGTTTATAAAATATTATGCGACCGGAGTAAAGCAAAGCTGAATTCCTGTGCCTACAAAATATCTAATTGAAAACACAAACAGCTGCCCGGTGTGTTAGATTTAATGTGCCCTGTGGATTAAGAGCAGGACCCTGGATATTAAGCAGAGAAGAGTCAATGCTCTCTGCCAGTCTTAGGCAGCAGTTTCTCAGCATTTCTCTGCAGAAAATGCAAAAGGTCACCACAATTTTTCTTTAATGCTGTAACATTGTGAGGGATGGGCTTCCCCCTGTCCAACTGATAAAGTGTTCCAAGAATCCTAAAACCCTTTGAAGAGCCAAGCACTGTTCA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| tbx4mq6/mq6 | Homozygous | ♀+/- ♂+/- | 5 figures from Don et al., 2011 | ||
| tbx4mq6/mq6 | Homozygous | Unknown | 3 figures  from Don et al., 2016 | Fig. 4 from Don et al., 2016 | |
| tbx4mq6/+ | Heterozygous | Unknown | Fig. 2 from Don et al., 2016 | ||
| tbx4mq6/+ | Heterozygous | Unknown | |||
| tbx4gi1/+; tbx4mq6/+ | Complex | Fig. 2 from Don et al., 2016 |
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Supplemental Information
- Genotyping protocol
- None
- Don, E.K., de Jong-Curtain, T.A., Doggett, K., Hall, T.E., Heng, B., Badrock, A.P., Winnick, C., Nicholson, G.A., Guillemin, G.J., Currie, P.D., Hesselson, D., Heath, J.K., Cole, N.J. (2016) Genetic basis of hindlimb loss in a naturally occurring vertebrate model. Biology Open. 5(3):359-66
- Don, E.K., Hall, T.E., Currie, P.D., and Cole, N.J. (2011) Morphology of pelvic fin loss in a zebrafish strain (Danio rerio). Journal of morphology. 272(5):583-589
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