Genomic Feature
fh131
- ID
- ZDB-ALT-120515-1
- Name
- fh131
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Moens Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 20: 30879788 (GRCz11) (1) Details
- Nucleotide change
- G/T
- Variant Notes
-
nucleotide substitution: G to T; mutated amino acid: E1219X
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- G>T (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- at position 1219 (1)
- Flanking Sequence
-
GTTCAGGCTTTAATAGTTCCTTCAGCCCTCCACCACCTCCCCCTCCACCACCACTGCCTACTTATTCTCCATCCCAAAATCAACATTTACCCCACATGACGCCACAAACACCTTCTTCTGCCTCCTTGAAAGAAATTAAGGGCTGTCTTAAACCAGTGAACTTAGAAGGAAGACCAGTGTTGCCTCAATCTGAGGAACCTAATAAGGTTAGCATGCCTTTGATTACCCCATTTGCACTGCAGAGTGTGCAGCTTCGGCCAGCAAAACGTCCAGAAAACAATGAAGTTAGCAGGACAGACAGACCCCAAACACCAGAAAAAACTCACCCCACAGTTCCTCAGATTTCTTGTATATCTCCAAATGTAAGCCTTTCATCTACAGAGGAAAAACCCTCAATCCAGCATAGCCAGGATGGCCTTGTTGAAGCACAAACTGACTATAGTGTAAAATCCAATTCTGATCCAACATCCTTCCTTACAAATGGGCCCATAGATCTTGGT
G/T AGGCCACAGATGAAGTAGATGGTTTAAAGACTTTCCTCTCAACACAAGTGGAAAAGTCACTAAACTCTACACCCAAGAAAAAGCCTCCAATGATTTCCAAAAAGCCCAAGTTTTCTCTTACTTTCTCCTCTGTGGATCATGTAAGGGATTTTGTGAGTGCTGAAGTTCTGGACCCCATACCTGTGCTGGAAAAAGAGGAAGAGACAACTGAGAAAAGTAGCTTTGACATTTCCGTACCTCCTGTAGAGATAAGAGACATTTCTCCCACAAATGGTGAATCTCAGGAGTTCTCACAATCCTCTGGTACCACTATTCTTGATGTAGACAAGAGCACCTCTGAAGCAGAGGATGAGGAAGAAAGAGATGACGAAGATGTAACCAGCAGCACAGGATCGTTCAGTTCTAAAGATGATGAAAATGGTGAGTTAGATTTTTCCTAATTTTACTCTGTGGGAATGGAGATCATTTATTACACTCAATGACACAAAGTCATACAATTT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| nhsl1bfh131/fh131 | Homozygous | ♀+/- ♂+/- | |||
| nhsl1bfh131/fh131 (AB/TU) | Homozygous | ♀+/- ♂+/- | |||
| nhsl1bfh131/+ (AB) | Heterozygous | ♀+/- ♂+/- | |||
| nhsl1bfh131/fh131; rw0Tg | Complex | Fig. 1  from Walsh et al., 2011 | 2 figures from Walsh et al., 2011 | ||
| nhsl1bfh131/fh131; rw0Tg | Complex | Fig. 1 from Walsh et al., 2011 | Fig. 1 from Walsh et al., 2011 | ||
| nhsl1bfh131/fh131; rw0Tg (AB/TU) | Complex | text only from Miller et al., 2013 | |||
| nhsl1bfh131/+; nhsl1bfh280/+; rw0Tg | Complex | Fig. 2 from Walsh et al., 2011 | Fig. 2 from Walsh et al., 2011 | ||
| nhsl1bfh131/+; rw0Tg | Complex | Fig. 2 from Walsh et al., 2011 | |||
| nhsl1bfh131/+; scribrw468/+; rw0Tg | Complex | Fig. 3 from Walsh et al., 2011 | Fig. 3 from Walsh et al., 2011 |
1 - 9 of 9
Show
Supplemental Information
- Genotyping protocol
- None
- Miller, A.C., Obholzer, N.D., Shah, A.N., Megason, S.G., and Moens, C.B. (2013) RNA-seq based mapping and candidate identification of mutations from forward genetic screens. Genome research. 23(4):679-686
- Walsh, G.S., Grant, P.K., Morgan, J.A., and Moens, C.B. (2011) Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration. Development (Cambridge, England). 138(14):3033-3042
1 - 2 of 2
Show