Genomic Feature
rw255
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 23: 17841117 (GRCz11) (1) Details
- Nucleotide change
- T/C
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>C (1)
- Transcript Consequence
- Missense (1)
- Protein Consequence
- Amino Acid Substitution: Phe>Ser at position 110 (1)
- Flanking Sequence
-
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTATATATATATATATATATATATATATATATATATATATATATATATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGTGTGTATGTGTGTGTGTAACAAAGTTACAAAGTTAAAATGTGATTAATCTTTTTTCTGCACTAATTATTATTTCTATTAAATAAATTACATTTTCTGAATAGTGGTTTTATTAAAAAAAATATTTTTTGTTGCTATGCTTTTACTATTATTTATTAATTATTTAATTTGCTGTAAATTATTAATTTCCATTCTCTTGAATTCCCCTTGATACATGATACTGTTTAATTTTATTACCAATGAAGAGATGATGTATTCTCTGCTTCTGTGATTGACAGCCCAGTCAACACAACACTGTGAAGTCTGGAACCTTCCAAGCCCTGGAAAAGGAACTGGTGT
T/C TGACATTGACATGACAGACTATGATGATGTCAGACGTTGCTGCAGGTTTACAGACGTTTGGTTTCTTTCATCTTTATACATATGATGCTTGTGCAATCATTCTGATTTTTAAAACTCATTATTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACACACACACACACACACACACACGCACACACACACACACACACACACACACACACACACACACACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACACACACATACACATATATACATACCTTTTTTGTGTTTAGTGCTGCTGACATCTGCTCGAAGTGCTGGACTCTAATGACCATCGCTATCCGCATTCTGGACCGGGCTCTTCGGGGTAAGCTGAATTTCTCATCTACAGAACATTTTCATTTTGAGTAA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| prim1rw255/rw255 (RW) | Homozygous | ♀+/- ♂+/- | 6 figures  from Yamaguchi et al., 2008 | Fig. 2 from Yamaguchi et al., 2008 | |
| prim1rw255/rw255; rw021Tg | Complex | Fig. 2 from Yamaguchi et al., 2008 | Fig. 2 from Yamaguchi et al., 2008 | ||
| prim1rw255/rw255 + MO1-atm (RW) | Complex | ||||
| prim1rw255/rw255 + MO1-atr (RW) | Complex | ||||
| prim1rw255/rw255 + MO1-chek1 (RW) | Complex | text only from Yamaguchi et al., 2008 | |||
| prim1rw255/rw255 + MO1-chek2 (RW) | Complex | 2 figures from Yamaguchi et al., 2008 | |||
| prim1rw255/rw255; smob577/b577 | Complex | Fig. 2 from Yamaguchi et al., 2008 | |||
| prim1rw255/rw255 + MO4-tp53 (RW) | Complex | 2 figures from Yamaguchi et al., 2008 |
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Supplemental Information
- Genotyping protocol
- None
- Nishiwaki, Y., Masai, I. (2020) β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors. Scientific Reports. 10:17379
- Yamaguchi, M., Fujimori-Tonou, N., Yoshimura, Y., Kishi, T., Okamoto, H., and Masai, I. (2008) Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development (Cambridge, England). 135(7):1247-1257
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