Genomic Feature
t21379
- ID
- ZDB-ALT-040715-4
- Name
- t21379
- Synonyms
-
- HX057UA (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Hammerschmidt Lab
- Current Source
-
European Zebrafish Resource Center (EZRC)
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Zebrafish International Resource Center (ZIRC) ( order this ) - Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 9: 19143847 (GRCz11) (1) Details
- Nucleotide change
- T/C
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- A>G (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
AAAAAATGATTTATTTTAATTGATTTTTAACTACTTAAACAGATAGTTCACCCAAAAATTACAATTCTGTCATATTTTACTCACCCTTCATTGTTTTAAACATTTATGACTTTCTTCTGTTAAACACAAGAGAAGACATTTTGAAAAATGTTGGAAACCTGTAACCATTGACTTCTATAGAATTAGTTTTTCCTACTATTGAAGTTAATGGTTACAGATTTCCAGCTTTTTCCAAAATACCTTATTTTGTGTTCAAAAGAAAGAAAAAAAAAAGAGACTCATGGTTTGCAACCACTTGAGGGGAAGTAAATAATGAGTCAATTTAAAATATTTGGGTGAACTGTCCGCTTTAATGGTGGTGCCATGGGGTTCAAAGTCTAGATTTAAGCACAGGCTGTACCTTGCAGTGAGTTGGCGCCATTAACCATGTTTGCATGAGGTACACTGCAGGTCTGCAGGATGCGGGTCTGGGAGATGCTGGCAGAGAGCATTTCCTGTGC
T/C GGAGATGCACACAAACACACGCACACACACATACACCACACTGTCATTTCACTCACACACACACAACATTAAGCCTGCATGCTTGTGTGTTTATTATGTTTATGCATAAAAGAGCAATGGTTGACGCAGTTGCAACTTGACGTACCTGCCATCATGCCGTAGGTGGTCTGCTGGTTGCTATAGTGACATGGGGGCATCGGGTAGTGGAGGCTGGCTGACGCATTGCCCAAAGCAGAAGTGGACAGGTGCATATGAGAGCGCTTGGACGACTGGACCAATGGGAGACCTGAGGGGACTAAAGAAGACACTAATATAAGTTATACTTGAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAAAAAAAAGAAAAAAAAAGGAAAAGAAAAAAGCACAAGAAAGAATATCAC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| pou1f1t21379/t21379 | Homozygous | Unknown | Fig. for (t21379) from Phenotype Annotation (1994-2006) | Fig. 5 from To et al., 2007 | |
| pou1f1t21379/+ (AB) | Heterozygous | Unknown |
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Supplemental Information
- Genotyping protocol
- None
- Dickmeis, T., Lahiri, K., Nica, G., Vallone, D., Santoriello, C., Neumann, C.J., Hammerschmidt, M., and Foulkes, N.S. (2007) Glucocorticoids Play a Key Role in Circadian Cell Cycle Rhythms. PLoS Biology. 5(4):e78
- To, T.T., Hahner, S., Nica, G., Rohr, K.B., Hammerschmidt, M., Winkler, C., and Allolio, B. (2007) Pituitary-interrenal interaction in zebrafish interrenal organ development. Molecular endocrinology (Baltimore, Md.). 21(2):472-485
- Herzog, W., Sonntag, C., Walderich, B., Odenthal, J., Maischein, H.M., and Hammerschmidt, M. (2004) Genetic analysis of adenohypophysis formation in zebrafish. Molecular endocrinology (Baltimore, Md.). 18(5):1185-1195
- Nica, G., Herzog, W., Sonntag, C., and Hammerschmidt, M. (2004) Zebrafish pit1 mutants lack three pituitary cell types and develop severe dwarfism. Molecular endocrinology (Baltimore, Md.). 18(5):1196-1209
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