RNA ligase (GTP) activity

Term ID

GO:0170057

Synonyms

• 3'-phosphate/5'-hydroxy nucleic acid ligase activity

Definition

Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H+. (2)

References

• EC:6.5.1.8
• MetaCyc:RXN-17905
• MetaCyc:RXN0-6566
• RHEA:68076
• RHEA:68080

Ontology

GO: Molecular Function    QuickGO    AmiGO