ATAC complex

Term ID

GO:0140672

Synonyms

• Ada two A containing complex
• ADA2A-containing complex
• G-ATAC complex
• KAT2A-containing ATAC complex
• KAT2B-containing ATAC complex

Definition

A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO