nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay

Term ID

GO:0070479

Synonyms

• 5'-3' NMD
• 5'-3' nonsense-mediated decay
• 5'-3' nonsense-mediated mRNA decay
• nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay
• nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay
• nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay

Definition

The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. 18554525

References

Ontology

GO: Biological Process    QuickGO    AmiGO