15-hydroxyprostaglandin dehydrogenase (NAD+) activity

Term ID

GO:0016404

Synonyms

• (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity
• 11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity
• 15-hydroxyprostaglandin dehydrogenase activity
• 15-hydroxyprostanoic dehydrogenase activity
• 15-OH-PGDH
• NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)
• NAD-specific 15-hydroxyprostaglandin dehydrogenase activity
• prostaglandin dehydrogenase activity

(all 8)

Definition

Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+. 1.1.1.141

References

• EC:1.1.1.141
• MetaCyc:1.1.1.141-RXN
• RHEA:11876
• Reactome:R-HSA-2161662
• Reactome:R-HSA-2161779
• Reactome:R-HSA-9023968
• Reactome:R-HSA-9024766

(all 7)

Ontology

GO: Molecular Function    QuickGO    AmiGO