protein O-linked glycosylation via N-acetyl-galactosamine

Term ID

GO:0016266

Synonyms

• core O-glycan biosynthetic process
• mucin-type O-glycan synthesis
• O-glycan processing
• protein O-linked GalNAcylation

Definition

A glycoprotein biosynthetic process starting with the covalent linkage of an N-acetyl-galactosamine via an alpha-glycosidic bond to the oxygen atom of a serine or threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan. (2)

References

• MetaCyc:PWY-7433
• MetaCyc:PWY-7435
• Reactome:R-HSA-913709

Ontology

GO: Biological Process    QuickGO    AmiGO