holo-[acyl-carrier-protein] synthase activity

Term ID

GO:0008897

Synonyms

• 4'-phosphopantetheinyl transferase activity
• 4'-phosphopantetheinyltransferase activity
• AcpS
• ACPS activity
• acyl carrier protein holoprotein (holo-ACP) synthetase activity
• acyl carrier protein synthase activity
• acyl carrier protein synthetase activity
• alpha-aminoadipate reductase phosphopantetheinyl transferase activity
• alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
• alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
• CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity
• CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity
• coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity
• holo-[peptidyl-carrier protein] synthase activity
• holo-ACP synthase activity
• holo-ACP synthetase activity
• holo-acyl-carrier-protein synthase activity
• holosynthase activity
• L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
• P-pant transferase activity
• phosphopantetheinyl transferase
• phosphopantetheinyltransferase activity
• PPTase activity

(all 23)

Definition

Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. (4)

References

• EC:2.7.8.7
• MetaCyc:HOLO-ACP-SYNTH-RXN
• RHEA:12068
• Reactome:R-HSA-199202

(all 4)

Ontology

GO: Molecular Function    QuickGO    AmiGO