(R,S)-4-hydroxy-2-oxoglutarate aldolase activity

Term ID

GO:0008700

Synonyms

• 2-keto-4-hydroxybutyrate aldolase activity
• 2-keto-4-hydroxyglutarate aldolase activity
• 2-keto-4-hydroxyglutaric aldolase activity
• 2-oxo-4-hydroxyglutarate aldolase activity
• 2-oxo-4-hydroxyglutaric aldolase activity
• 4-hydroxy-2-ketoglutarate aldolase activity
• 4-hydroxy-2-ketoglutaric aldolase activity
• 4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)
• 4-hydroxy-2-oxoglutarate glyoxylate-lyase activity
• DL-4-hydroxy-2-ketoglutarate aldolase activity
• hydroxyketoglutarate aldolase activity
• hydroxyketoglutaric aldolase activity
• KHG-aldolase activity

Definition

Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. Can act on both the (4R) and the (4S) enantiomers of 4-hydroxy-2-oxoglutarate. 4.1.3.16

References

• EC:4.1.3.16
• MetaCyc:4OH2OXOGLUTARALDOL-RXN
• RHEA:18169
• Reactome:R-HSA-6784423

Ontology

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