GABA shunt

Term ID

GO:0006540

Synonyms

• 4-aminobutyrate shunt
• gamma aminobutyrate shunt
• gamma-aminobutyrate shunt
• glutamate decarboxylation to succinate

Definition

The chemical reactions and pathways resulting in the formation of succinate from L-glutamate via gamma-aminobutyrate (GABA), bypassing two steps of the TCA cycle. It operates through the sequential conversion of glutamate to GABA by glutamate decarboxylase, transamination of GABA to succinic semialdehyde by GABA transaminase, and oxidation of succinic semialdehyde to succinate by succinate semialdehyde dehydrogenase. 39703920

References

• MetaCyc:GLUDEG-I-PWY
• MetaCyc:PWY-8346

Ontology

GO: Biological Process    QuickGO    AmiGO