DNA endonuclease activity

Term ID

GO:0004520

Synonyms

DNA nicking activity
endodeoxyribonuclease activity
endonuclease G activity

Definition

Catalysis of the cleavage of ester linkages within deoxyribonucleic acid by creating internal breaks. 0198547684

References

Reactome:R-HSA-110359
Reactome:R-HSA-5686440
Reactome:R-HSA-5686657
Reactome:R-HSA-5687464
Reactome:R-HSA-5690988
Reactome:R-HSA-5693584
Reactome:R-HSA-5693608
Reactome:R-HSA-6782204
Reactome:R-HSA-6782224
Reactome:R-HSA-9023941

(all 10)

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: DNA nuclease activity endonuclease activity

DNA nuclease activity endonuclease activity Show first 5 Terms
has subtype: deoxyribonuclease (pyrimidine dimer) activity DNA endonuclease activity, producing 3'-phosphomonoesters DNA endonuclease activity, producing 5'-phosphomonoesters DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA endonuclease activity ... Show All 11 Terms

deoxyribonuclease (pyrimidine dimer) activity DNA endonuclease activity, producing 3'-phosphomonoesters DNA endonuclease activity, producing 5'-phosphomonoesters DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA endonuclease activity excinuclease ABC activity flap endonuclease activity restriction endodeoxyribonuclease activity retroviral 3' processing activity single-stranded DNA endodeoxyribonuclease activity T/G mismatch-specific endonuclease activity Show first 5 Terms
inverse has_part: removal of nonhomologous ends

removal of nonhomologous ends Show first 5 Terms
negatively regulated by: negative regulation of endodeoxyribonuclease activity

negative regulation of endodeoxyribonuclease activity Show first 5 Terms
positively regulated by: endodeoxyribonuclease activator activity positive regulation of endodeoxyribonuclease activity

endodeoxyribonuclease activator activity positive regulation of endodeoxyribonuclease activity Show first 5 Terms
regulated by: regulation of endodeoxyribonuclease activity

regulation of endodeoxyribonuclease activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Include Normal Phenotypes