mRNA 5'-cap (guanine-N7-)-methyltransferase activity

Term ID

GO:0004482

Synonyms

• guanine-7-methyltransferase activity
• messenger ribonucleate guanine 7-methyltransferase activity
• messenger RNA guanine 7-methyltransferase activity
• S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity
• S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity

Definition

Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine. 2.1.1.56

References

• EC:2.1.1.56
• MetaCyc:MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN
• Reactome:R-HSA-77090
• Reactome:R-HSA-9684016
• Reactome:R-HSA-9684017
• Reactome:R-HSA-9684018
• Reactome:R-HSA-9694476
• Reactome:R-HSA-9694492
• Reactome:R-HSA-9694737
• Reactome:R-HSA-9830848

Ontology

GO: Molecular Function    QuickGO    AmiGO